Abstract
Osteoporosis is one of the most common bone-related disorders in the elderly. It is a complex disease, and largely determined genetically. Traditional gene expression studies have shown that osteoporosis has complex regulating mechanisms which are controlled by multiple inherent factors, such as hormones, cytokines, various receptors, etc. The complex nature of osteoporosis, and the large number of genes involved in its onset and development, suggest the use of the state of the art microarray technique as a powerful tool to unravel mechanisms underlying etiology of osteoporosis.
| Original language | English |
|---|---|
| Pages (from-to) | 451-461 |
| Number of pages | 11 |
| Journal | Osteoporosis International |
| Volume | 14 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jul 1 2003 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Gene expression studies of osteoporosis : Implications for microarray research. / Dvornyk, V.; Recker, Robert R.; Deng, H. W.
In: Osteoporosis International, Vol. 14, No. 6, 01.07.2003, p. 451-461.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Gene expression studies of osteoporosis
T2 - Implications for microarray research
AU - Dvornyk, V.
AU - Recker, Robert R.
AU - Deng, H. W.
PY - 2003/7/1
Y1 - 2003/7/1
N2 - Osteoporosis is one of the most common bone-related disorders in the elderly. It is a complex disease, and largely determined genetically. Traditional gene expression studies have shown that osteoporosis has complex regulating mechanisms which are controlled by multiple inherent factors, such as hormones, cytokines, various receptors, etc. The complex nature of osteoporosis, and the large number of genes involved in its onset and development, suggest the use of the state of the art microarray technique as a powerful tool to unravel mechanisms underlying etiology of osteoporosis.
AB - Osteoporosis is one of the most common bone-related disorders in the elderly. It is a complex disease, and largely determined genetically. Traditional gene expression studies have shown that osteoporosis has complex regulating mechanisms which are controlled by multiple inherent factors, such as hormones, cytokines, various receptors, etc. The complex nature of osteoporosis, and the large number of genes involved in its onset and development, suggest the use of the state of the art microarray technique as a powerful tool to unravel mechanisms underlying etiology of osteoporosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0043208695&partnerID=8YFLogxK
U2 - 10.1007/s00198-002-1373-0
DO - 10.1007/s00198-002-1373-0
M3 - Review article
C2 - 12730742
AN - SCOPUS:0043208695
VL - 14
SP - 451
EP - 461
JO - Osteoporosis International
JF - Osteoporosis International
SN - 0937-941X
IS - 6
ER -