Gene manipulation and genetic toxicology

Raymond W. Tennant, Laura A. Hansen, Judson Spalding

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Transgenic mice with recoverable target genes, with genes modified in expression or with ablated gene function provide important tools for defining the biological effects of chemicals. In many cases studies can be conducted with fewer animals and in a shorter timeframe. They also provide important tools for studies of carcinogenesis mechanisms and processes, for early detection of carcinogens and for identification of potential cancer therapies.

Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalMutagenesis
Volume9
Issue number3
DOIs
StatePublished - 1994
Externally publishedYes

Fingerprint

Toxicology
Manipulation
Genes
Gene
Transgenic Mice
Carcinogens
Carcinogenesis
Therapy
Animals
Cancer
Target
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Genetics
  • Health, Toxicology and Mutagenesis
  • Genetics(clinical)
  • Toxicology
  • Statistics, Probability and Uncertainty
  • Applied Mathematics

Cite this

Gene manipulation and genetic toxicology. / Tennant, Raymond W.; Hansen, Laura A.; Spalding, Judson.

In: Mutagenesis, Vol. 9, No. 3, 1994, p. 171-174.

Research output: Contribution to journalArticle

Tennant, Raymond W. ; Hansen, Laura A. ; Spalding, Judson. / Gene manipulation and genetic toxicology. In: Mutagenesis. 1994 ; Vol. 9, No. 3. pp. 171-174.
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