Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi, H. Miyagawa, Devendra K. Agrawal, Againdra K. Bewtra, R. G. Townley

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Abstract

We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.

Original languageEnglish
Pages (from-to)228-232
Number of pages5
JournalAnnals of Allergy
Volume65
Issue number3
Publication statusPublished - 1990

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All Science Journal Classification (ASJC) codes

  • Immunology and Allergy

Cite this

Kohi, F., Miyagawa, H., Agrawal, D. K., Bewtra, A. K., & Townley, R. G. (1990). Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects. Annals of Allergy, 65(3), 228-232.