Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi, H. Miyagawa, D. K. Agrawal, A. K. Bewtra, R. G. Townley

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.

Original languageEnglish (US)
Pages (from-to)228-232
Number of pages5
JournalAnnals of allergy
Volume65
Issue number3
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy

Fingerprint Dive into the research topics of 'Generation of leukotriene B<sub>4</sub> and C<sub>4</sub> from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects'. Together they form a unique fingerprint.

Cite this