Abstract
Hereditary Breast Cancer (HBC) poses a major public health problem wherein about 10% of the total breast cancer burden is due to primary genetic factors. The bulk of hereditary breast cancer is extremely heterogeneous, as evidenced by at least eight to ten differing HBC syndromes, such as hereditary breast/ovarian cancer (HBOC), the Li-Fraumeni (SBLA) syndrome, Cowden's disease, Bloom's syndrome, and heterozygotes with the ataxia telangiectasia gene. This extant heterogeneity must be carefully appraised when evaluating patients at risk for HBC. Screening ang management must be melded carefully to HBC's natural history. Genetic counseling plays a crucial part in the overall management of HBC, particularly when DNA testing is under consideration.
| Original language | French |
|---|---|
| Pages (from-to) | 85-89 |
| Number of pages | 5 |
| Journal | Sein |
| Volume | 6 |
| Issue number | 2 |
| State | Published - Jun 20 1996 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Surgery
Cite this
Genetique et maladie du sein. / Lynch, Henry T.; Lynch, F.
In: Sein, Vol. 6, No. 2, 20.06.1996, p. 85-89.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetique et maladie du sein
AU - Lynch, Henry T.
AU - Lynch, F.
PY - 1996/6/20
Y1 - 1996/6/20
N2 - Hereditary Breast Cancer (HBC) poses a major public health problem wherein about 10% of the total breast cancer burden is due to primary genetic factors. The bulk of hereditary breast cancer is extremely heterogeneous, as evidenced by at least eight to ten differing HBC syndromes, such as hereditary breast/ovarian cancer (HBOC), the Li-Fraumeni (SBLA) syndrome, Cowden's disease, Bloom's syndrome, and heterozygotes with the ataxia telangiectasia gene. This extant heterogeneity must be carefully appraised when evaluating patients at risk for HBC. Screening ang management must be melded carefully to HBC's natural history. Genetic counseling plays a crucial part in the overall management of HBC, particularly when DNA testing is under consideration.
AB - Hereditary Breast Cancer (HBC) poses a major public health problem wherein about 10% of the total breast cancer burden is due to primary genetic factors. The bulk of hereditary breast cancer is extremely heterogeneous, as evidenced by at least eight to ten differing HBC syndromes, such as hereditary breast/ovarian cancer (HBOC), the Li-Fraumeni (SBLA) syndrome, Cowden's disease, Bloom's syndrome, and heterozygotes with the ataxia telangiectasia gene. This extant heterogeneity must be carefully appraised when evaluating patients at risk for HBC. Screening ang management must be melded carefully to HBC's natural history. Genetic counseling plays a crucial part in the overall management of HBC, particularly when DNA testing is under consideration.
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UR - http://www.scopus.com/inward/citedby.url?scp=0030036603&partnerID=8YFLogxK
M3 - Article
VL - 6
SP - 85
EP - 89
JO - Imagerie de la Femme
JF - Imagerie de la Femme
SN - 1776-9817
IS - 2
ER -