Has Vitamin D had its "time in the sun" for melanoma?

Christopher Huerter, Adam Vaudreuil, Devendra K. Agrawal, Austin Huy Nguyen

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Growing evidence suggests a pivotal role for Vitamin D in cancers, particularly melanoma. The broad immunologic effects of Vitamin D and its signaling axis make for a complex interplay between tumor cells and the immune system. Preclinical evidence suggests Vitamin D to have protective effects in melanoma oncogenesis and progression, creating a potential role for Vitamin D supplementation in cancer prevention and/or adjuvant therapy. In this commentary, the authors highlight studies of Vitamin D in melanoma with clinical implications and call for large clinical trials to definitively determine the role of supplementation in patients to prevent and help treat melanoma.

Original languageEnglish (US)
Pages (from-to)11-12
Number of pages2
JournalJournal of Clinical and Aesthetic Dermatology
Volume9
Issue number12
StatePublished - Dec 1 2016

All Science Journal Classification (ASJC) codes

  • Dermatology

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