Heart Failure With Preserved Ejection Fraction

Selma F. Mohammed, Niti R. Aggarwal, Ajith P. Nair, Anita Deswal

Research output: Chapter in Book/Report/Conference proceedingChapter


Heart failure with preserved ejection fraction (HFpEF) is the most common type of heart failure (HF) in women and increases in prevalence with age. HFpEF is associated with multiple cardiovascular and noncardiovascular comorbidities. Diagnosis of HFpEF is challenging and effective disease-modifying therapies are lacking. HFpEF is associated with poor outcomes and is an area of unmet needs. In this chapter, we will review the epidemiology, pathophysiology, clinical presentation, diagnostic approach, prognosis, and management of patients with HFpEF with emphasis on differences by sex. We will also summarize key points and future directions for practicing clinicians and researchers in the field of HFpEF.

Original languageEnglish (US)
Title of host publicationSex Differences in Cardiac Diseases
Subtitle of host publicationPathophysiology, Presentation, Diagnosis and Management
Number of pages22
ISBN (Electronic)9780128193693
StatePublished - Jan 1 2021

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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