The use of dietary supplements in North America has exploded over the last two decades. Some of the most commonly used supplements include multiple vitamins; B vitamins; vitamins C, E, and D; valerian; chamomile; garlic; ginkgo; St. John’s wort; evening primrose oil; soy; aloe; and echinacea. Many patients do not disclose their use of supplements to their healthcare providers. This is problematic because many supplements have the potential to interact with medications used during the perioperative period or in an acute care setting. Interactions can be either pharmacodynamic or pharmacokinetic. The level of evidence supporting these interactions varies substantially, ranging from in vitro studies to findings from reliable pharmacokinetic trials. In order to maintain patient safety, incorporating supplement-specific questions into patient interviews is crucial. Dietary supplements should be discontinued 2 weeks before elective surgical procedures to avoid potential perioperative complications.
|Original language||English (US)|
|Title of host publication||Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care|
|Publisher||Springer New York|
|Number of pages||14|
|State||Published - Jan 1 2015|
All Science Journal Classification (ASJC) codes