Heterogeneity and natural history of hereditary breast cancer: Surgical implications

Henry T. Lynch, Robert Joseph Fitzgibbons, J. F. Lynch

Research output: Contribution to journalReview article

14 Scopus citations


The properly compiled cancer family history can prove to be one of the most cost-effective and powerful instruments for cancer control in breast cancer. Needed, however, is an understanding of the heterogeneity of hereditary breast cancer and knowledge of those facets of its natural history that can expedite an syndrome diagnosis. Priority concerns for cancer control in hereditary breast cancer are the development of registries of cancerprone families, willingness by third-party carriers to help defray the costs of surveillance, and more research in molecular genetics.

Original languageEnglish
Pages (from-to)753-774
Number of pages22
JournalSurgical Clinics of North America
Issue number4
StatePublished - 1990


All Science Journal Classification (ASJC) codes

  • Surgery

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