HL A in cancer family 'N'

Henry T. Lynch, R. J. Thomas, P. I. Terasaki, A. Ting, H. A. Guirgis, A. R. Kaplan, H. Magee, J. Lynch, C. Kraft, E. Chaperon

Research output: Contribution to journalArticle

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Abstract

Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1,000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer prone line (branches C and D) of the family, 20 of 21 members with cancer had 1 HL-A haplotype, HL-A2-HL-A12 (relative odds = 6.30), including some deceased family members who had haplotypes assigned. 11 Of 12 family members with cancer in branches C and D, actually typed, had HL-A2-HL-A12 (relative odds = 6.06). The single exception showing cancer and another haplotype in branch D is a child of a family member with haplotype HL-A2-HL-A12.

Original languageEnglish
Pages (from-to)1315-1320
Number of pages6
JournalCancer
Volume36
Issue number4
DOIs
StatePublished - 1975

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Haplotypes
compound A 12
varespladib methyl
Neoplasms
Odds Ratio

All Science Journal Classification (ASJC) codes

  • Cancer Research
  • Oncology

Cite this

Lynch, H. T., Thomas, R. J., Terasaki, P. I., Ting, A., Guirgis, H. A., Kaplan, A. R., ... Chaperon, E. (1975). HL A in cancer family 'N'. Cancer, 36(4), 1315-1320. https://doi.org/10.1002/1097-0142(197510)36:4<1315::AID-CNCR2820360419>3.0.CO;2-T

HL A in cancer family 'N'. / Lynch, Henry T.; Thomas, R. J.; Terasaki, P. I.; Ting, A.; Guirgis, H. A.; Kaplan, A. R.; Magee, H.; Lynch, J.; Kraft, C.; Chaperon, E.

In: Cancer, Vol. 36, No. 4, 1975, p. 1315-1320.

Research output: Contribution to journalArticle

Lynch, HT, Thomas, RJ, Terasaki, PI, Ting, A, Guirgis, HA, Kaplan, AR, Magee, H, Lynch, J, Kraft, C & Chaperon, E 1975, 'HL A in cancer family 'N'', Cancer, vol. 36, no. 4, pp. 1315-1320. https://doi.org/10.1002/1097-0142(197510)36:4<1315::AID-CNCR2820360419>3.0.CO;2-T
Lynch HT, Thomas RJ, Terasaki PI, Ting A, Guirgis HA, Kaplan AR et al. HL A in cancer family 'N'. Cancer. 1975;36(4):1315-1320. https://doi.org/10.1002/1097-0142(197510)36:4<1315::AID-CNCR2820360419>3.0.CO;2-T
Lynch, Henry T. ; Thomas, R. J. ; Terasaki, P. I. ; Ting, A. ; Guirgis, H. A. ; Kaplan, A. R. ; Magee, H. ; Lynch, J. ; Kraft, C. ; Chaperon, E. / HL A in cancer family 'N'. In: Cancer. 1975 ; Vol. 36, No. 4. pp. 1315-1320.
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AU - Kaplan, A. R.

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