Abstract
Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1,000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer prone line (branches C and D) of the family, 20 of 21 members with cancer had 1 HL-A haplotype, HL-A2-HL-A12 (relative odds = 6.30), including some deceased family members who had haplotypes assigned. 11 Of 12 family members with cancer in branches C and D, actually typed, had HL-A2-HL-A12 (relative odds = 6.06). The single exception showing cancer and another haplotype in branch D is a child of a family member with haplotype HL-A2-HL-A12.
Original language | English (US) |
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Pages (from-to) | 1315-1320 |
Number of pages | 6 |
Journal | Cancer |
Volume | 36 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1975 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research