Abstract
Strain typing is an integral part of epidemiological investigations of nosocomial infections. Methods for distinguishing among bacterial strains have improved dramatically over the last 5 years, due mainly to the introduction of molecular technology. Although not all molecular techniques are equally effective for typing all organisms, pulsed-field gel electrophoresis is the technique currently favored for most nosocomial pathogens. Criteria to aid epidemiologists in interpreting results have been published. Nucleic acid amplification-based typing methods also are applicable to many organisms and can be completed within a single day, but interpretive criteria still are under debate. Strain typing cannot be used to replace a sound epidemiological investigation, but serves as a useful adjunct to such investigations.
| Original language | English |
|---|---|
| Pages (from-to) | 426-439 |
| Number of pages | 14 |
| Journal | Infection Control and Hospital Epidemiology |
| Volume | 18 |
| Issue number | 6 |
| State | Published - Jun 1997 |
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All Science Journal Classification (ASJC) codes
- Immunology
- Microbiology (medical)
Cite this
How to Select and Interpret Molecular Strain Typing Methods for Epidemiological Studies of Bacterial Infections : A Review for Healthcare Epidemiologists. / Tenover, Fred C.; Arbeit, Robert D.; Goering, Richard V.; Murray, Barbara E.; Persing, David H.; Pfaller, Michael A.; Weinstein, Robert A.
In: Infection Control and Hospital Epidemiology, Vol. 18, No. 6, 06.1997, p. 426-439.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - How to Select and Interpret Molecular Strain Typing Methods for Epidemiological Studies of Bacterial Infections
T2 - A Review for Healthcare Epidemiologists
AU - Tenover, Fred C.
AU - Arbeit, Robert D.
AU - Goering, Richard V.
AU - Murray, Barbara E.
AU - Persing, David H.
AU - Pfaller, Michael A.
AU - Weinstein, Robert A.
PY - 1997/6
Y1 - 1997/6
N2 - Strain typing is an integral part of epidemiological investigations of nosocomial infections. Methods for distinguishing among bacterial strains have improved dramatically over the last 5 years, due mainly to the introduction of molecular technology. Although not all molecular techniques are equally effective for typing all organisms, pulsed-field gel electrophoresis is the technique currently favored for most nosocomial pathogens. Criteria to aid epidemiologists in interpreting results have been published. Nucleic acid amplification-based typing methods also are applicable to many organisms and can be completed within a single day, but interpretive criteria still are under debate. Strain typing cannot be used to replace a sound epidemiological investigation, but serves as a useful adjunct to such investigations.
AB - Strain typing is an integral part of epidemiological investigations of nosocomial infections. Methods for distinguishing among bacterial strains have improved dramatically over the last 5 years, due mainly to the introduction of molecular technology. Although not all molecular techniques are equally effective for typing all organisms, pulsed-field gel electrophoresis is the technique currently favored for most nosocomial pathogens. Criteria to aid epidemiologists in interpreting results have been published. Nucleic acid amplification-based typing methods also are applicable to many organisms and can be completed within a single day, but interpretive criteria still are under debate. Strain typing cannot be used to replace a sound epidemiological investigation, but serves as a useful adjunct to such investigations.
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M3 - Article
VL - 18
SP - 426
EP - 439
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
SN - 0899-823X
IS - 6
ER -