Abstract
The cfr gene was identified in three linezolid-resistant USA300 methicillin-resistant Staphylococcus aureus (MRSA) isolates collected over a 3-day period at a New York City medical center in 2011 as part of a routine surveillance program. Each isolate possessed a plasmid containing a pSCFS3-like cfr gene environment. Transformation of the cfr-bearing plasmids into the S. aureus ATCC 29213 background recapitulated the expected Cfr antibiogram, including resistance to linezolid, tiamulin, clindamycin, and florfenicol and susceptibility to tedizolid.
| Original language | English |
|---|---|
| Pages (from-to) | 6949-6952 |
| Number of pages | 4 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 58 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2014 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Pharmacology
- Infectious Diseases
Cite this
Identification and characterization of linezolid-resistant cfr-positive staphylococcus aureus USA300 Isolates from a new york city medical center. / Locke, Jeffrey B.; Zuill, Douglas E.; Scharn, Caitlyn R.; Deane, Jennifer; Sahm, Daniel F.; Goering, Richard V.; Jenkins, Stephen G.; Shaw, Karen J.
In: Antimicrobial Agents and Chemotherapy, Vol. 58, No. 11, 01.11.2014, p. 6949-6952.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Identification and characterization of linezolid-resistant cfr-positive staphylococcus aureus USA300 Isolates from a new york city medical center
AU - Locke, Jeffrey B.
AU - Zuill, Douglas E.
AU - Scharn, Caitlyn R.
AU - Deane, Jennifer
AU - Sahm, Daniel F.
AU - Goering, Richard V.
AU - Jenkins, Stephen G.
AU - Shaw, Karen J.
PY - 2014/11/1
Y1 - 2014/11/1
N2 - The cfr gene was identified in three linezolid-resistant USA300 methicillin-resistant Staphylococcus aureus (MRSA) isolates collected over a 3-day period at a New York City medical center in 2011 as part of a routine surveillance program. Each isolate possessed a plasmid containing a pSCFS3-like cfr gene environment. Transformation of the cfr-bearing plasmids into the S. aureus ATCC 29213 background recapitulated the expected Cfr antibiogram, including resistance to linezolid, tiamulin, clindamycin, and florfenicol and susceptibility to tedizolid.
AB - The cfr gene was identified in three linezolid-resistant USA300 methicillin-resistant Staphylococcus aureus (MRSA) isolates collected over a 3-day period at a New York City medical center in 2011 as part of a routine surveillance program. Each isolate possessed a plasmid containing a pSCFS3-like cfr gene environment. Transformation of the cfr-bearing plasmids into the S. aureus ATCC 29213 background recapitulated the expected Cfr antibiogram, including resistance to linezolid, tiamulin, clindamycin, and florfenicol and susceptibility to tedizolid.
UR - http://www.scopus.com/inward/record.url?scp=84908596733&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908596733&partnerID=8YFLogxK
U2 - 10.1128/AAC.03380-14
DO - 10.1128/AAC.03380-14
M3 - Article
C2 - 25136008
AN - SCOPUS:84908596733
VL - 58
SP - 6949
EP - 6952
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 11
ER -