Abstract
(3H)Nitrendipine binding to the bovine tracheal muscle membrane at 25°C was rapid, saturable (Bmax=14.8±3.9fmol/mg protein) and of high affinity (Kd=0.15±0.04 nM). The rank order of Ca2+ antagonists competing for airway (3H)nitrendipine binding was nitrendipine {Mathematical expression} nisoldipine {Mathematical expression} nifedipine » verapamil. Cromolyn, however, neither inhibited nor increased the binding.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 267-269 |
| Number of pages | 3 |
| Journal | Experientia |
| Volume | 40 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 1984 |
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
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Cheng, J. B., Bewtra, A., & Townley, R. G. (1984). Identification of calcium antagonist receptor binding sites using (3H)nitrendipine in bovine tracheal smooth muscle membranes. Experientia, 40(3), 267-269. https://doi.org/10.1007/BF01947575