Abstract
Identifying individuals who have Lynch syndrome (LS) involves a complex diagnostic work up that includes taking a detailed family history and a combination of various genetic and immunohistochemical tests. The National Society of Genetic Counselors (NSGC) and the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC) have come together to publish this clinical practice testing guideline for the evaluation of LS. The purpose of this practice guideline is to provide guidance and a testing algorithm for LS as well as recommendations on when to offer testing. This guideline does not replace a consultation with a genetics professional. This guideline includes explanations in support of this and a summary of background data. While this guideline is not intended to serve as a review of LS, it includes a discussion of background information on LS, and cites a number of key publications which should be reviewed for a more in-depth understanding of LS. These guidelines are intended for genetic counselors, geneticists, gastroenterolo-gists, surgeons, medical oncologists, obstetricians and gynecologists, nurses and other healthcare providers who evaluate patients for LS.
| Original language | English |
|---|---|
| Pages (from-to) | 484-493 |
| Number of pages | 10 |
| Journal | Journal of Genetic Counseling |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2012 |
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All Science Journal Classification (ASJC) codes
- Genetics(clinical)
Cite this
Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing : National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline. / Weissman, Scott M.; Burt, Randall; Church, James; Erdman, Steve; Hampel, Heather; Holter, Spring; Jasperson, Kory; Kalady, Matt F.; Haidle, Joy Larsen; Lynch, Henry T.; Palaniappan, Selvi; Wise, Paul E.; Senter, Leigha.
In: Journal of Genetic Counseling, Vol. 21, No. 4, 08.2012, p. 484-493.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing
T2 - National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline
AU - Weissman, Scott M.
AU - Burt, Randall
AU - Church, James
AU - Erdman, Steve
AU - Hampel, Heather
AU - Holter, Spring
AU - Jasperson, Kory
AU - Kalady, Matt F.
AU - Haidle, Joy Larsen
AU - Lynch, Henry T.
AU - Palaniappan, Selvi
AU - Wise, Paul E.
AU - Senter, Leigha
PY - 2012/8
Y1 - 2012/8
N2 - Identifying individuals who have Lynch syndrome (LS) involves a complex diagnostic work up that includes taking a detailed family history and a combination of various genetic and immunohistochemical tests. The National Society of Genetic Counselors (NSGC) and the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC) have come together to publish this clinical practice testing guideline for the evaluation of LS. The purpose of this practice guideline is to provide guidance and a testing algorithm for LS as well as recommendations on when to offer testing. This guideline does not replace a consultation with a genetics professional. This guideline includes explanations in support of this and a summary of background data. While this guideline is not intended to serve as a review of LS, it includes a discussion of background information on LS, and cites a number of key publications which should be reviewed for a more in-depth understanding of LS. These guidelines are intended for genetic counselors, geneticists, gastroenterolo-gists, surgeons, medical oncologists, obstetricians and gynecologists, nurses and other healthcare providers who evaluate patients for LS.
AB - Identifying individuals who have Lynch syndrome (LS) involves a complex diagnostic work up that includes taking a detailed family history and a combination of various genetic and immunohistochemical tests. The National Society of Genetic Counselors (NSGC) and the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC) have come together to publish this clinical practice testing guideline for the evaluation of LS. The purpose of this practice guideline is to provide guidance and a testing algorithm for LS as well as recommendations on when to offer testing. This guideline does not replace a consultation with a genetics professional. This guideline includes explanations in support of this and a summary of background data. While this guideline is not intended to serve as a review of LS, it includes a discussion of background information on LS, and cites a number of key publications which should be reviewed for a more in-depth understanding of LS. These guidelines are intended for genetic counselors, geneticists, gastroenterolo-gists, surgeons, medical oncologists, obstetricians and gynecologists, nurses and other healthcare providers who evaluate patients for LS.
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UR - http://www.scopus.com/inward/citedby.url?scp=84863609627&partnerID=8YFLogxK
U2 - 10.1007/s10897-011-9465-7
DO - 10.1007/s10897-011-9465-7
M3 - Review article
VL - 21
SP - 484
EP - 493
JO - Journal of Genetic Counseling
JF - Journal of Genetic Counseling
SN - 1059-7700
IS - 4
ER -