TY - JOUR
T1 - Immature teratoma associated with anti–N-methyl-D-aspartate receptor encephalitis
AU - Malayev, Yuliya
AU - Alberts, Jared
AU - Verardi, Mary Ann
AU - Mattison, Anissa R.
AU - Imlay, Sherwin
N1 - Publisher Copyright:
© 2015 American Osteopathic Association.
PY - 2015/9
Y1 - 2015/9
N2 - Gynecologic teratomas commonly present with pelvic symptoms. The authors report a case of teratoma causing acute psychosis, encephalopathy, and sudden-onset seizures in a previously healthy 33-year-old woman. After common organic causes were excluded, investigation revealed an immature teratoma containing brain tissue on her left ovary. Anti–N-methyl-d-aspartate receptor encephalitis was diagnosed and, with excision and medical management, her symptoms resolved and she was discharged home in stable condition. Encephalopathy is not commonly attributed to gynecologic causes, but anti–N-methyl-d-aspartate receptor encephalitis may be caused by ovarian teratomas with a neuronal component. Thorough gynecologic examination should be performed on any female patient presenting with new-onset psychosis, encephalopathy, and seizures, especially in the absence of other organic or structural causes. Thus, it is important to look at the whole patient and not just the symptoms.
AB - Gynecologic teratomas commonly present with pelvic symptoms. The authors report a case of teratoma causing acute psychosis, encephalopathy, and sudden-onset seizures in a previously healthy 33-year-old woman. After common organic causes were excluded, investigation revealed an immature teratoma containing brain tissue on her left ovary. Anti–N-methyl-d-aspartate receptor encephalitis was diagnosed and, with excision and medical management, her symptoms resolved and she was discharged home in stable condition. Encephalopathy is not commonly attributed to gynecologic causes, but anti–N-methyl-d-aspartate receptor encephalitis may be caused by ovarian teratomas with a neuronal component. Thorough gynecologic examination should be performed on any female patient presenting with new-onset psychosis, encephalopathy, and seizures, especially in the absence of other organic or structural causes. Thus, it is important to look at the whole patient and not just the symptoms.
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U2 - 10.7556/jaoa.2015.116
DO - 10.7556/jaoa.2015.116
M3 - Article
C2 - 26322937
AN - SCOPUS:84956533473
VL - 115
SP - 573
EP - 577
JO - The Journal of the American Osteopathic Association
JF - The Journal of the American Osteopathic Association
SN - 0098-6151
IS - 9
ER -