In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong; Ellen Smith Moland; Paul A. Wickman; Jennifer A. Black; Ashfaque Hossain; Nancy D. Hanson; Kenneth S. Thomson

doi:10.1128/AAC.00959-06

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong, Ellen Smith Moland, Paul A. Wickman, Jennifer A. Black, Ashfaque Hossain, Nancy D. Hanson, Kenneth S. Thomson

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

Original language	English
Pages (from-to)	1512-1514
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	51
Issue number	4
DOIs	https://doi.org/10.1128/AAC.00959-06
Publication status	Published - Apr 2007

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All Science Journal Classification (ASJC) codes

Pharmacology (medical)

Cite this

Hong, S. G., Moland, E. S., Wickman, P. A., Black, J. A., Hossain, A., Hanson, N. D., & Thomson, K. S. (2007). In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. Antimicrobial Agents and Chemotherapy, 51(4), 1512-1514. https://doi.org/10.1128/AAC.00959-06

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. / Hong, Seong Geun; Moland, Ellen Smith; Wickman, Paul A.; Black, Jennifer A.; Hossain, Ashfaque; Hanson, Nancy D.; Thomson, Kenneth S.

In: Antimicrobial Agents and Chemotherapy, Vol. 51, No. 4, 04.2007, p. 1512-1514.

Research output: Contribution to journal › Article

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10.1128/AAC.00959-06