In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong; Ellen Smith Moland; Paul A. Wickman; Jennifer A. Black; Ashfaque Hossain; Nancy D. Hanson; Kenneth S. Thomson

doi:10.1128/AAC.00959-06

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong, Ellen Smith Moland, Paul A. Wickman, Jennifer A. Black, Ashfaque Hossain, Nancy D. Hanson, Kenneth S. Thomson

Department of Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

Original language	English (US)
Pages (from-to)	1512-1514
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	51
Issue number	4
DOIs	https://doi.org/10.1128/AAC.00959-06
State	Published - Apr 2007

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)
Infectious Diseases

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In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. / Hong, Seong Geun; Moland, Ellen Smith; Wickman, Paul A.; Black, Jennifer A.; Hossain, Ashfaque; Hanson, Nancy D.; Thomson, Kenneth S.

In: Antimicrobial agents and chemotherapy, Vol. 51, No. 4, 04.2007, p. 1512-1514.

Research output: Contribution to journal › Article › peer-review

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abstract = "DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.",

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AU - Black, Jennifer A.

AU - Hossain, Ashfaque

AU - Hanson, Nancy D.

AU - Thomson, Kenneth S.

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In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Abstract

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