In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong, Ellen Smith Moland, Paul A. Wickman, Jennifer A. Black, Ashfaque Hossain, Nancy D. Hanson, Kenneth S. Thomson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

Original languageEnglish
Pages (from-to)1512-1514
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume51
Issue number4
DOIs
StatePublished - Apr 2007

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Gram-Positive Cocci
Fluoroquinolones
Enterococcus
Streptococcus pneumoniae
Staphylococcus
Levofloxacin
Ciprofloxacin
In Vitro Techniques
DQ113
moxifloxacin
sitafloxacin

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. / Hong, Seong Geun; Moland, Ellen Smith; Wickman, Paul A.; Black, Jennifer A.; Hossain, Ashfaque; Hanson, Nancy D.; Thomson, Kenneth S.

In: Antimicrobial Agents and Chemotherapy, Vol. 51, No. 4, 04.2007, p. 1512-1514.

Research output: Contribution to journalArticle

Hong, Seong Geun ; Moland, Ellen Smith ; Wickman, Paul A. ; Black, Jennifer A. ; Hossain, Ashfaque ; Hanson, Nancy D. ; Thomson, Kenneth S. / In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci. In: Antimicrobial Agents and Chemotherapy. 2007 ; Vol. 51, No. 4. pp. 1512-1514.
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