In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci

Seong Geun Hong, Ellen Smith Moland, Paul A. Wickman, Jennifer A. Black, Ashfaque Hossain, Nancy D. Hanson, Kenneth S. Thomson

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Abstract

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

Original languageEnglish
Pages (from-to)1512-1514
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume51
Issue number4
DOIs
Publication statusPublished - Apr 2007

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All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

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