In-vivo measurement of osteoporotic bone fragility with apparent velocity of ultrasound

G. Brandenburger, L. Avioli, C. Chesnut, R. Heaney, R. Poss, G. Pratt, Robert R. Recker

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Loss of mechanical strength due to bone conditions such as osteoporosis causes spontaneous fractures despite the absence of significant physical trauma. Well-established theory and in vitro experiment suggest the potential for ultrasound velocity to assess such deterioration of bone strength. Nevertheless, technical obstacles have precluded in vivo application until recently. A novel approach is described for achieving accuracy and reproducibility by overcoming difficulties with inhomogeneity, anisotropy, overlying soft tissue, and multipath propagation. Key elements of the design include anatomical-site selection, propagation-path determination, ultrasound generation and detection, digital signal processing, and apparent-velocity estimation.

Original languageEnglish
Pages (from-to)1023-1027
Number of pages5
JournalUnknown Journal
Volume2
Publication statusPublished - 1989

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All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Brandenburger, G., Avioli, L., Chesnut, C., Heaney, R., Poss, R., Pratt, G., & Recker, R. R. (1989). In-vivo measurement of osteoporotic bone fragility with apparent velocity of ultrasound. Unknown Journal, 2, 1023-1027.