Abstract
Loss of mechanical strength due to bone conditions such as osteoporosis causes spontaneous fractures despite the absence of significant physical trauma. Well-established theory and in vitro experiment suggest the potential for ultrasound velocity to assess such deterioration of bone strength. Nevertheless, technical obstacles have precluded in vivo application until recently. A novel approach is described for achieving accuracy and reproducibility by overcoming difficulties with inhomogeneity, anisotropy, overlying soft tissue, and multipath propagation. Key elements of the design include anatomical-site selection, propagation-path determination, ultrasound generation and detection, digital signal processing, and apparent-velocity estimation.
| Original language | English |
|---|---|
| Pages (from-to) | 1023-1027 |
| Number of pages | 5 |
| Journal | Unknown Journal |
| Volume | 2 |
| State | Published - 1989 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
In-vivo measurement of osteoporotic bone fragility with apparent velocity of ultrasound. / Brandenburger, G.; Avioli, L.; Chesnut, C.; Heaney, R.; Poss, R.; Pratt, G.; Recker, Robert R.
In: Unknown Journal, Vol. 2, 1989, p. 1023-1027.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - In-vivo measurement of osteoporotic bone fragility with apparent velocity of ultrasound
AU - Brandenburger, G.
AU - Avioli, L.
AU - Chesnut, C.
AU - Heaney, R.
AU - Poss, R.
AU - Pratt, G.
AU - Recker, Robert R.
PY - 1989
Y1 - 1989
N2 - Loss of mechanical strength due to bone conditions such as osteoporosis causes spontaneous fractures despite the absence of significant physical trauma. Well-established theory and in vitro experiment suggest the potential for ultrasound velocity to assess such deterioration of bone strength. Nevertheless, technical obstacles have precluded in vivo application until recently. A novel approach is described for achieving accuracy and reproducibility by overcoming difficulties with inhomogeneity, anisotropy, overlying soft tissue, and multipath propagation. Key elements of the design include anatomical-site selection, propagation-path determination, ultrasound generation and detection, digital signal processing, and apparent-velocity estimation.
AB - Loss of mechanical strength due to bone conditions such as osteoporosis causes spontaneous fractures despite the absence of significant physical trauma. Well-established theory and in vitro experiment suggest the potential for ultrasound velocity to assess such deterioration of bone strength. Nevertheless, technical obstacles have precluded in vivo application until recently. A novel approach is described for achieving accuracy and reproducibility by overcoming difficulties with inhomogeneity, anisotropy, overlying soft tissue, and multipath propagation. Key elements of the design include anatomical-site selection, propagation-path determination, ultrasound generation and detection, digital signal processing, and apparent-velocity estimation.
UR - http://www.scopus.com/inward/record.url?scp=0024871752&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024871752&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024871752
VL - 2
SP - 1023
EP - 1027
JO - Nuclear Physics A
JF - Nuclear Physics A
SN - 0375-9474
ER -