@inproceedings{035dc957be36481eb1b8702b3831fc14,
title = "In vivo strain application in rat tibiae using non-invasive loading method",
abstract = "This study characterized a non-invasive method of applying mechanical strain to the tibiae of rats. A four-point bending device was used to induce mechanical strain non-invasively in an 11 mm section of the right tibiae of 10 female Sprague-Dawley rats. Induced strains were measured in vivo at various locations along the rat tibia to establish a relationship between induced strain and applied load. Finite element analysis was used to quantify the magnitude of shear stresses in the rat tibia due to four-point bending. The in vivo measured strains were highly correlated with the calculated strains using beam bending theory (r2 = 0.87). The finite element model predicted shear stresses to be less than 10 percent of the longitudinal stresses resulting from the four-point bending.",
author = "Akhter, {M. P.} and Raab, {D. M.} and Turner, {C. H.} and Kimmel, {D. B.} and Recker, {R. R.}",
year = "1991",
month = dec,
day = "1",
language = "English (US)",
isbn = "0791808890",
series = "American Society of Mechanical Engineers, Bioengineering Division (Publication) BED",
publisher = "Publ by ASME",
pages = "353--355",
booktitle = "1991 Advances in Bioengineering",
note = "Winter Annual Meeting of the American Society of Mechanical Engineers ; Conference date: 01-12-1991 Through 06-12-1991",
}