Abstract
Higher serum 25-hydroxyvitamin D [25(OH)D] concentrations have been associated with lower risk of type 2 diabetes. This study compared incidence rates of type 2 diabetes among participants aged ≥20 years in two U.S. cohorts with markedly different median 25(OH)D concentrations. The median 25(OH)D concentration in the GrassrootsHealth (GRH) cohort was 41 ng/ml (N = 4933) while in the 2005-6 National Health and Nutrition Examination Survey (NHANES) it was 22 ng/ml (N = 4078) (P <0.0001). The adjusted annual incidence rate of type 2 diabetes was 3.7 per 1000 population (95% confidence interval = 1.9, 6.6) in the GRH cohort, compared to 9.3 per 1000 population (95% confidence interval = 6.7, 12.6) in NHANES. In the NHANES cohort, the lowest 25(OH)D tertiles (
Original language | English (US) |
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Pages (from-to) | 239-244 |
Number of pages | 6 |
Journal | Journal of Steroid Biochemistry and Molecular Biology |
Volume | 155 |
DOIs | |
State | Published - Jan 1 2016 |
All Science Journal Classification (ASJC) codes
- Endocrinology, Diabetes and Metabolism
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Endocrinology
- Clinical Biochemistry
- Cell Biology