@inbook{eef806fbe94f45cfbd6b66a6ab3fba71,
title = "Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: The 'canary in the coal mine' during exercise-heat stress?",
abstract = "Reduced intestinal blood flow and high intestinal temperatures during exercise-heat stress can lead to intestinal barrier dysfunction. Such dysfunction may increase intestinal permeability to endotoxin. During exercise-heat stress, intestinal barrier dysfunction and endotoxemia can produce gastrointestinal symptoms and increased production of pro-inflammatory cytokines. Such problems may be a warning sign ('canary in the coal mine') for the onset of exertional heat stroke. Failure to heed such a warning may culminate in problems indicative of exertional heat stroke such as circulatory collapse and multiple organ failure. Prior exposure to exercise-heat stress may, however, be a protective mechanism.",
author = "Lambert, {G. Patrick}",
year = "2008",
month = aug,
day = "29",
doi = "10.1159/000151550",
language = "English (US)",
isbn = "9783805586481",
series = "Medicine and Sport Science",
pages = "61--73",
booktitle = "Thermoregulation and Human Performance",
}