Intestinal fluid absorption during exercise

Role of sport drink osmolality and [Na+]

C. V. Gisolfi, G. Patrick Lambert, R. W. Summers

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the effects of modifying the osmolality and [Na+] of orally ingested rehydration beverages during exercise on intestinal absorption in the duodenum and upper jejunum. Six subjects randomly ingested (23 mL·kg-1 BW) the following 6% carbohydrate solutions with and without Na+ during 85-min of cycle exercise (65% VO2 peak) in a cool (22°C, 40% RH) environment: a) 0 Na+, 245 mOsm·kg-1; b) 20 mEq Na+, 283 mOsm·kg-1; c) 20 mEq Na+, 169 mOsm·kg-1; d) 50 mEq Na+, 275 mOsm·kg-1; and e) 50 mEq Na+, 176 mOsm·kg-1. To alter solution osmolality and maintain carbohydrate concentration constant, glucose, sucrose, fructose, and maltodextrin were used in different combinations. Nasogastric and multilumen tubes were fluoroscopically placed in the stomach and intestine, respectively, to simultaneously determine gastric emptying and intestinal absorption as previously described (Lambert et al., Int. J. Sports Med. 17:48, 1996). Gastric emptying was not different among solutions and averaged 13 ± 0.5 mL·min-1. Net fluid absorption was not different among beverages nor between duodenum and jejunum (x = 10.8 ± 1.6 and 7.9 ± 1.1 mL·cm-1h-1, respectively). Mean osmolality increased significantly (P < 0.05) from the duodenum to the jejunum (242 ± 6 and 293 ± 7 mOsm·kg-1, respectively) but did not differ among solutions. These data provide evidence that a hypotonic 6% carbohydrate beverage with 50 mEq·L-1 Na+ did not enhance intestinal fluid absorption or attenuate the decline in plasma volume during exercise more than an isotonic carbohydrate-electrolyte solution or a hypotonic carbohydrate solution without sodium.

Original languageEnglish (US)
Pages (from-to)907-915
Number of pages9
JournalMedicine and Science in Sports and Exercise
Volume33
Issue number6
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

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Intestinal Absorption
Osmolar Concentration
Sports
Carbohydrates
Beverages
Jejunum
Duodenum
Gastric Emptying
Hypotonic Solutions
Plasma Volume
Fluid Therapy
Fructose
Electrolytes
Intestines
Sucrose
Stomach
Sodium
Glucose

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Intestinal fluid absorption during exercise : Role of sport drink osmolality and [Na+]. / Gisolfi, C. V.; Lambert, G. Patrick; Summers, R. W.

In: Medicine and Science in Sports and Exercise, Vol. 33, No. 6, 01.01.2001, p. 907-915.

Research output: Contribution to journalArticle

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