Intoxication with Fireball Whiskey causing severe lactic acidosis

Research output: Contribution to journalArticlepeer-review

Abstract

Propylene glycol is a viscous, colorless liquid that has been approved by the US Food and Drug Administration for use as a preservative in foods and as a solvent in pharmaceuticals. Compared with methanol and ethylene glycol, it is regarded as a relatively safe alcohol. There have been several reports of severe lactic acidosis in the setting of iatrogenic unintentional overdosing of medications that use propylene glycol as a diluent, including lorazepam and diazepam. The laboratory findings may include high metabolic acidosis and high osmolal gap. Propylene glycol is also one of the ingredients used in Fireball Whiskey. We present two cases of severe lactic acidosis in the setting of Fireball Whiskey use.

Original languageEnglish (US)
Pages (from-to)521-522
Number of pages2
JournalBaylor University Medical Center Proceedings
Volume34
Issue number4
DOIs
StatePublished - 2021

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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