Intra-H-2 recombination in H-2^b/H-2^t1 heterozygotes in the mouse - II. Characterization of recombinant haplotypes at2, at3, and at4

Four cases of intra-H-2 recombination were detected during serological screening of 1066 backcross animals produced from H-2^b/H-2^t1 heterozygous mice. Three of the intra -H-2 recombinants received the K region from H-2^t1 and the D region from the H-2^b parental chromosome. The remaining recombinant received the K region from the H-2^b parental chromosome and the D region from H-2^t1. Three of the four recombinants have been developed into inbred lines TBR2, TBR3, and TBR4 and were assigned the haplotype designations at², at³, and at⁴. Ss typing revealed that TBR2 and TBR3 originated from K- S interval crossover events, while the remaining two recombinants resulted from crossing over in the S- D interval.