Intra‐H‐2 Recombination in H‐2b/H‐2t1 Heterozygotes in the Mouse I. Four Cases of Crossing Over between the S and D Regions

Howard C. Passmore; Kirk W. Beisel

doi:10.1111/j.1399-0039.1977.tb01091.x

Intra‐H‐2 Recombination in H‐2^b/H‐2^t¹ Heterozygotes in the Mouse I. Four Cases of Crossing Over between the S and D Regions

Howard C. Passmore, Kirk W. Beisel

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

An examination of 1009 backcross animals produced from H-2b/H-2t1 heterozygotes resulted in the detection of four cases of intra-H-2 recombination. Three of the recombinants received the K region from H-2b and the D region from the H-2t1 parental chromosome. The fourth recombinant received a K region from the H-2t1 parental chromosome and the D region from H-2b. Ss typing revealed that crossing occurred between the S and D regions of the H-2 complex in all four cases. Three of the four recombinants were developed into inbred strains and assigned the halotype designations H-218, H-2i9 and H2at1.

Original language	English (US)
Pages (from-to)	121-130
Number of pages	10
Journal	Tissue Antigens
Volume	9
Issue number	2
DOIs	https://doi.org/10.1111/j.1399-0039.1977.tb01091.x
State	Published - Feb 1977
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Biochemistry
Genetics

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10.1111/j.1399-0039.1977.tb01091.x

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title = "Intra‐H‐2 Recombination in H‐2b/H‐2t1 Heterozygotes in the Mouse I. Four Cases of Crossing Over between the S and D Regions",

abstract = "An examination of 1009 backcross animals produced from H-2b/H-2t1 heterozygotes resulted in the detection of four cases of intra-H-2 recombination. Three of the recombinants received the K region from H-2b and the D region from the H-2t1 parental chromosome. The fourth recombinant received a K region from the H-2t1 parental chromosome and the D region from H-2b. Ss typing revealed that crossing occurred between the S and D regions of the H-2 complex in all four cases. Three of the four recombinants were developed into inbred strains and assigned the halotype designations H-218, H-2i9 and H2at1.",

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AB - An examination of 1009 backcross animals produced from H-2b/H-2t1 heterozygotes resulted in the detection of four cases of intra-H-2 recombination. Three of the recombinants received the K region from H-2b and the D region from the H-2t1 parental chromosome. The fourth recombinant received a K region from the H-2t1 parental chromosome and the D region from H-2b. Ss typing revealed that crossing occurred between the S and D regions of the H-2 complex in all four cases. Three of the four recombinants were developed into inbred strains and assigned the halotype designations H-218, H-2i9 and H2at1.

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Intra‐H‐2 Recombination in H‐2^b/H‐2^t¹ Heterozygotes in the Mouse I. Four Cases of Crossing Over between the S and D Regions

Abstract

All Science Journal Classification (ASJC) codes

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