Abstract
An examination of 1009 backcross animals produced from H-2b/H-2t1 heterozygotes resulted in the detection of four cases of intra-H-2 recombination. Three of the recombinants received the K region from H-2b and the D region from the H-2t1 parental chromosome. The fourth recombinant received a K region from the H-2t1 parental chromosome and the D region from H-2b. Ss typing revealed that crossing occurred between the S and D regions of the H-2 complex in all four cases. Three of the four recombinants were developed into inbred strains and assigned the halotype designations H-218, H-2i9 and H2at1.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 121-130 |
| Number of pages | 10 |
| Journal | Tissue Antigens |
| Volume | 9 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1977 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology
- Biochemistry
- Genetics
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Passmore, H. C., & Beisel, K. W. (1977). Intra‐H‐2 Recombination in H‐2b/H‐2t1 Heterozygotes in the Mouse I. Four Cases of Crossing Over between the S and D Regions. Tissue Antigens, 9(2), 121-130. https://doi.org/10.1111/j.1399-0039.1977.tb01091.x