Intraoperative modality of treatment for peritoneal carcinomatosis

Use of hyperthermic interperitoneal chemoperfusion

S. W. Sutton, L. W. Yancey, V. A. Chase, E. K. Hunley, T. M. McCarty, J. A. Kuhn, Brian W. Loggie

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The use of hyperthermia as an adjunct to chemotherapy in the treatment of peritoneal carcinomatosis is a promising technique for patients who otherwise have a poor prognosis for survival. We, herein, report an overview and description of our technique for the safe conduct of this treatment. Included in these data are a total of 71 patients who underwent an intraoperative treatment with Mitomycin C at temperatures of 41-42°C for a 90- to 120-min time period. The treatment protocol, perfusion system description, technical considerations, and potential complications are also included. The prognosis for intraabdominal carcinomatosis is poor with conventional treatments and modalities. We believe that the use of this technique offers a very positive clinical alternative for patients undergoing treatment for laparoscopic palliation of malignant ascites and/or surgical debulking for intraoperative treatment and prevention of metastasis.

Original languageEnglish
Pages (from-to)441-446
Number of pages6
JournalPerfusion
Volume17
Issue number6
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Patient treatment
Chemotherapy
Carcinoma
Temperature
Therapeutics
Mitomycin
Clinical Protocols
Ascites
Fever
Perfusion
Neoplasm Metastasis
Drug Therapy
Survival
time

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Intraoperative modality of treatment for peritoneal carcinomatosis : Use of hyperthermic interperitoneal chemoperfusion. / Sutton, S. W.; Yancey, L. W.; Chase, V. A.; Hunley, E. K.; McCarty, T. M.; Kuhn, J. A.; Loggie, Brian W.

In: Perfusion, Vol. 17, No. 6, 2002, p. 441-446.

Research output: Contribution to journalArticle

Sutton, S. W. ; Yancey, L. W. ; Chase, V. A. ; Hunley, E. K. ; McCarty, T. M. ; Kuhn, J. A. ; Loggie, Brian W. / Intraoperative modality of treatment for peritoneal carcinomatosis : Use of hyperthermic interperitoneal chemoperfusion. In: Perfusion. 2002 ; Vol. 17, No. 6. pp. 441-446.
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