Abstract
The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic contrast agents were compared in rats to study potentially harmful peritoneal inflammation. Only intraperitoneal barium injection produced any significant tissue reaction, such as adhesions and ascites. There was no difference between iopamidol and the other water-soluble contrast agents. Iopamidol may satisfy the need for nonreactive and nearly iso-osmolar contrast agents for evaluating patients with possible bowel perforation. However, the high cost of this agent may make its clinical application impractical.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 141-145 |
| Number of pages | 5 |
| Journal | Investigative Radiology |
| Volume | 25 |
| Issue number | 2 |
| State | Published - 1990 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
Cite this
Iopamidol as a gastrointestinal contrast agent : Lack of peritoneal reactivity. / Ferrante, Stephen L.; Schreiman, Judith S.; Rouse, Jonathan W.; Rysavy, Joseph A.; Cheng, Shih-Chuan; Frick, Mathis P.
In: Investigative Radiology, Vol. 25, No. 2, 1990, p. 141-145.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Iopamidol as a gastrointestinal contrast agent
T2 - Lack of peritoneal reactivity
AU - Ferrante, Stephen L.
AU - Schreiman, Judith S.
AU - Rouse, Jonathan W.
AU - Rysavy, Joseph A.
AU - Cheng, Shih-Chuan
AU - Frick, Mathis P.
PY - 1990
Y1 - 1990
N2 - The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic contrast agents were compared in rats to study potentially harmful peritoneal inflammation. Only intraperitoneal barium injection produced any significant tissue reaction, such as adhesions and ascites. There was no difference between iopamidol and the other water-soluble contrast agents. Iopamidol may satisfy the need for nonreactive and nearly iso-osmolar contrast agents for evaluating patients with possible bowel perforation. However, the high cost of this agent may make its clinical application impractical.
AB - The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic contrast agents were compared in rats to study potentially harmful peritoneal inflammation. Only intraperitoneal barium injection produced any significant tissue reaction, such as adhesions and ascites. There was no difference between iopamidol and the other water-soluble contrast agents. Iopamidol may satisfy the need for nonreactive and nearly iso-osmolar contrast agents for evaluating patients with possible bowel perforation. However, the high cost of this agent may make its clinical application impractical.
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M3 - Article
VL - 25
SP - 141
EP - 145
JO - Investigative Radiology
JF - Investigative Radiology
SN - 0020-9996
IS - 2
ER -