Is sialography effective in diagnosing the salivary component of Sjögren's syndrome?

T. E. Daniels, Douglas Benn

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Parotid sialography has been used for many years as a means of assessing salivary glands in Sjögren's syndrome (SS), and it is occasionally used as a diagnostic criterion for the salivary component of SS. To assess its diagnostic effectiveness, we reviewed studies in which sialography was applied to patients with SS and control subjects for the purpose of estimating its diagnostic sensitivity and specificity or comparing it with other means of assessing salivary glands. Sialography appears to be diagnostically less sensitive but more specific than salivary flow rate measurement and more sensitive but less specific than labial salivary gland (LSG) biopsy. Such calculations are based on the diagnosis of SS established in each study, but the various studies used widely different criteria to establish that diagnosis. Therefore, these calculations are not based on a consistent standard, and comparison between the calculations may be misleading, which underscores the need to develop internationally accepted diagnostic criteria for SS. Studies conducted so far have not shown that parotid sialography is either a sensitive indicator of the salivary component of SS or more closely associated than LSG biopsy with keratoconjunctivitis sicca, the only other component of primary SS with which ultimately to assess diagnostic specificity.

Original languageEnglish
Pages (from-to)25-28
Number of pages4
JournalAdvances in dental research
Volume10
Issue number1
StatePublished - Apr 1996
Externally publishedYes

Fingerprint

Sialography
Salivary Glands
Lip
Keratoconjunctivitis Sicca
Biopsy
Sensitivity and Specificity

Cite this

Is sialography effective in diagnosing the salivary component of Sjögren's syndrome? / Daniels, T. E.; Benn, Douglas.

In: Advances in dental research, Vol. 10, No. 1, 04.1996, p. 25-28.

Research output: Contribution to journalReview article

@article{d748510b8dac401ab7bc1d162d6d3197,
title = "Is sialography effective in diagnosing the salivary component of Sj{\"o}gren's syndrome?",
abstract = "Parotid sialography has been used for many years as a means of assessing salivary glands in Sj{\"o}gren's syndrome (SS), and it is occasionally used as a diagnostic criterion for the salivary component of SS. To assess its diagnostic effectiveness, we reviewed studies in which sialography was applied to patients with SS and control subjects for the purpose of estimating its diagnostic sensitivity and specificity or comparing it with other means of assessing salivary glands. Sialography appears to be diagnostically less sensitive but more specific than salivary flow rate measurement and more sensitive but less specific than labial salivary gland (LSG) biopsy. Such calculations are based on the diagnosis of SS established in each study, but the various studies used widely different criteria to establish that diagnosis. Therefore, these calculations are not based on a consistent standard, and comparison between the calculations may be misleading, which underscores the need to develop internationally accepted diagnostic criteria for SS. Studies conducted so far have not shown that parotid sialography is either a sensitive indicator of the salivary component of SS or more closely associated than LSG biopsy with keratoconjunctivitis sicca, the only other component of primary SS with which ultimately to assess diagnostic specificity.",
author = "Daniels, {T. E.} and Douglas Benn",
year = "1996",
month = "4",
language = "English",
volume = "10",
pages = "25--28",
journal = "Advances in dental research",
issn = "0895-9374",
publisher = "International Association for Dental Research",
number = "1",

}

TY - JOUR

T1 - Is sialography effective in diagnosing the salivary component of Sjögren's syndrome?

AU - Daniels, T. E.

AU - Benn, Douglas

PY - 1996/4

Y1 - 1996/4

N2 - Parotid sialography has been used for many years as a means of assessing salivary glands in Sjögren's syndrome (SS), and it is occasionally used as a diagnostic criterion for the salivary component of SS. To assess its diagnostic effectiveness, we reviewed studies in which sialography was applied to patients with SS and control subjects for the purpose of estimating its diagnostic sensitivity and specificity or comparing it with other means of assessing salivary glands. Sialography appears to be diagnostically less sensitive but more specific than salivary flow rate measurement and more sensitive but less specific than labial salivary gland (LSG) biopsy. Such calculations are based on the diagnosis of SS established in each study, but the various studies used widely different criteria to establish that diagnosis. Therefore, these calculations are not based on a consistent standard, and comparison between the calculations may be misleading, which underscores the need to develop internationally accepted diagnostic criteria for SS. Studies conducted so far have not shown that parotid sialography is either a sensitive indicator of the salivary component of SS or more closely associated than LSG biopsy with keratoconjunctivitis sicca, the only other component of primary SS with which ultimately to assess diagnostic specificity.

AB - Parotid sialography has been used for many years as a means of assessing salivary glands in Sjögren's syndrome (SS), and it is occasionally used as a diagnostic criterion for the salivary component of SS. To assess its diagnostic effectiveness, we reviewed studies in which sialography was applied to patients with SS and control subjects for the purpose of estimating its diagnostic sensitivity and specificity or comparing it with other means of assessing salivary glands. Sialography appears to be diagnostically less sensitive but more specific than salivary flow rate measurement and more sensitive but less specific than labial salivary gland (LSG) biopsy. Such calculations are based on the diagnosis of SS established in each study, but the various studies used widely different criteria to establish that diagnosis. Therefore, these calculations are not based on a consistent standard, and comparison between the calculations may be misleading, which underscores the need to develop internationally accepted diagnostic criteria for SS. Studies conducted so far have not shown that parotid sialography is either a sensitive indicator of the salivary component of SS or more closely associated than LSG biopsy with keratoconjunctivitis sicca, the only other component of primary SS with which ultimately to assess diagnostic specificity.

UR - http://www.scopus.com/inward/record.url?scp=0030114985&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030114985&partnerID=8YFLogxK

M3 - Review article

C2 - 8934919

AN - SCOPUS:0030114985

VL - 10

SP - 25

EP - 28

JO - Advances in dental research

JF - Advances in dental research

SN - 0895-9374

IS - 1

ER -