A case report is presented of a patient with Klinefelter's syndrome in whom breast cancer developed. The patient was in the direct genetic lineage of a cancer-prone family. Follow-up was maintained from the time his breast cancer was diagnosed until his death from metastases 12 years later. From our experience and from reports in literature, we recommend that patients with Klinefelter's syndrome be considered prime candidates for prophylactic total mastectomy, particularly in the presence of a family history of cancer. Intensive surveillance should be considered for those Klinefelter's patients who decline breast surgery.
|Original language||English (US)|
|Number of pages||2|
|Journal||Breast. Diseases of the Breast|
|State||Published - Jan 1 1985|
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