Abstract
A second trimester sonographic diagnosis of twins discordant for lethal osteogenesis imperfecta is reported. A 29 year old primigravida was referred for an ultrasonogram at 20 weeks and 2 days' gestation after a 24 cm fundal height was noted. Examination revealed an intrauterine dichorionic twin pregnancy. The male fetus was appropriately grown with sonographically normal anatomy. The hypoechoic and compressible calvarium of the female co-twin permitted unusually clear visualization of the intracranial anatomy. This fetus exhibited multiply fractured femora, one of which measured 1.6 a cm in length, tetramicromelia, and a hypoechoic skeleton. Accurate and timely diagnosis of the type II osteogenesis imperfecta allowed the parents to be counseled appropriately and the pregnancy managed in accordance with the well-being of the viable co-twin.
| Original language | English |
|---|---|
| Pages (from-to) | 711-713 |
| Number of pages | 3 |
| Journal | Journal of Ultrasound in Medicine |
| Volume | 13 |
| Issue number | 9 |
| State | Published - Sep 1994 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Acoustics and Ultrasonics
- Radiological and Ultrasound Technology
Cite this
Lethal osteogenesis imperfecta : Second trimester sonographic diagnosis in a twin gestation. / Wax, J. R.; Smith, Jr., James; Floyd, R. C.
In: Journal of Ultrasound in Medicine, Vol. 13, No. 9, 09.1994, p. 711-713.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lethal osteogenesis imperfecta
T2 - Second trimester sonographic diagnosis in a twin gestation
AU - Wax, J. R.
AU - Smith, Jr., James
AU - Floyd, R. C.
PY - 1994/9
Y1 - 1994/9
N2 - A second trimester sonographic diagnosis of twins discordant for lethal osteogenesis imperfecta is reported. A 29 year old primigravida was referred for an ultrasonogram at 20 weeks and 2 days' gestation after a 24 cm fundal height was noted. Examination revealed an intrauterine dichorionic twin pregnancy. The male fetus was appropriately grown with sonographically normal anatomy. The hypoechoic and compressible calvarium of the female co-twin permitted unusually clear visualization of the intracranial anatomy. This fetus exhibited multiply fractured femora, one of which measured 1.6 a cm in length, tetramicromelia, and a hypoechoic skeleton. Accurate and timely diagnosis of the type II osteogenesis imperfecta allowed the parents to be counseled appropriately and the pregnancy managed in accordance with the well-being of the viable co-twin.
AB - A second trimester sonographic diagnosis of twins discordant for lethal osteogenesis imperfecta is reported. A 29 year old primigravida was referred for an ultrasonogram at 20 weeks and 2 days' gestation after a 24 cm fundal height was noted. Examination revealed an intrauterine dichorionic twin pregnancy. The male fetus was appropriately grown with sonographically normal anatomy. The hypoechoic and compressible calvarium of the female co-twin permitted unusually clear visualization of the intracranial anatomy. This fetus exhibited multiply fractured femora, one of which measured 1.6 a cm in length, tetramicromelia, and a hypoechoic skeleton. Accurate and timely diagnosis of the type II osteogenesis imperfecta allowed the parents to be counseled appropriately and the pregnancy managed in accordance with the well-being of the viable co-twin.
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M3 - Article
VL - 13
SP - 711
EP - 713
JO - Journal of Ultrasound in Medicine
JF - Journal of Ultrasound in Medicine
SN - 0278-4297
IS - 9
ER -