Lethal osteogenesis imperfecta: Second trimester sonographic diagnosis in a twin gestation

J. R. Wax, James Smith, Jr., R. C. Floyd

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A second trimester sonographic diagnosis of twins discordant for lethal osteogenesis imperfecta is reported. A 29 year old primigravida was referred for an ultrasonogram at 20 weeks and 2 days' gestation after a 24 cm fundal height was noted. Examination revealed an intrauterine dichorionic twin pregnancy. The male fetus was appropriately grown with sonographically normal anatomy. The hypoechoic and compressible calvarium of the female co-twin permitted unusually clear visualization of the intracranial anatomy. This fetus exhibited multiply fractured femora, one of which measured 1.6 a cm in length, tetramicromelia, and a hypoechoic skeleton. Accurate and timely diagnosis of the type II osteogenesis imperfecta allowed the parents to be counseled appropriately and the pregnancy managed in accordance with the well-being of the viable co-twin.

Original languageEnglish
Pages (from-to)711-713
Number of pages3
JournalJournal of Ultrasound in Medicine
Volume13
Issue number9
StatePublished - Sep 1994

Fingerprint

osteogenesis
Osteogenesis Imperfecta
anatomy
pregnancy
fetuses
Second Pregnancy Trimester
Anatomy
Fetus
femur
Pregnancy
Twin Pregnancy
musculoskeletal system
Skull
Skeleton
Femur
examination

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Acoustics and Ultrasonics
  • Radiological and Ultrasound Technology

Cite this

Lethal osteogenesis imperfecta : Second trimester sonographic diagnosis in a twin gestation. / Wax, J. R.; Smith, Jr., James; Floyd, R. C.

In: Journal of Ultrasound in Medicine, Vol. 13, No. 9, 09.1994, p. 711-713.

Research output: Contribution to journalArticle

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