Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11

W. J. Kimberling, C. G. Möller, S. Davenport, I. A. Priluck, P. H. Beighton, J. Greenberg, W. Reardon, Michael Weston, J. B. Kenyon, J. A. Grunkemeyer, S. Pieke Dahl, L. D. Overbeck, D. J. Blackwood, A. M. Brower, D. M. Hoover, P. Rowland, R. J H Smith

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.

Original languageEnglish
Pages (from-to)988-994
Number of pages7
JournalGenomics
Volume14
Issue number4
DOIs
StatePublished - 1992
Externally publishedYes

Fingerprint

Usher Syndromes
Chromosomes, Human, Pair 11
Genes
Chromosomes
Hearing Loss
Developed Countries
Organism Cloning
Phenotype

All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Kimberling, W. J., Möller, C. G., Davenport, S., Priluck, I. A., Beighton, P. H., Greenberg, J., ... Smith, R. J. H. (1992). Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11. Genomics, 14(4), 988-994. https://doi.org/10.1016/S0888-7543(05)80121-1

Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11. / Kimberling, W. J.; Möller, C. G.; Davenport, S.; Priluck, I. A.; Beighton, P. H.; Greenberg, J.; Reardon, W.; Weston, Michael; Kenyon, J. B.; Grunkemeyer, J. A.; Pieke Dahl, S.; Overbeck, L. D.; Blackwood, D. J.; Brower, A. M.; Hoover, D. M.; Rowland, P.; Smith, R. J H.

In: Genomics, Vol. 14, No. 4, 1992, p. 988-994.

Research output: Contribution to journalArticle

Kimberling, WJ, Möller, CG, Davenport, S, Priluck, IA, Beighton, PH, Greenberg, J, Reardon, W, Weston, M, Kenyon, JB, Grunkemeyer, JA, Pieke Dahl, S, Overbeck, LD, Blackwood, DJ, Brower, AM, Hoover, DM, Rowland, P & Smith, RJH 1992, 'Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11', Genomics, vol. 14, no. 4, pp. 988-994. https://doi.org/10.1016/S0888-7543(05)80121-1
Kimberling WJ, Möller CG, Davenport S, Priluck IA, Beighton PH, Greenberg J et al. Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11. Genomics. 1992;14(4):988-994. https://doi.org/10.1016/S0888-7543(05)80121-1
Kimberling, W. J. ; Möller, C. G. ; Davenport, S. ; Priluck, I. A. ; Beighton, P. H. ; Greenberg, J. ; Reardon, W. ; Weston, Michael ; Kenyon, J. B. ; Grunkemeyer, J. A. ; Pieke Dahl, S. ; Overbeck, L. D. ; Blackwood, D. J. ; Brower, A. M. ; Hoover, D. M. ; Rowland, P. ; Smith, R. J H. / Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11. In: Genomics. 1992 ; Vol. 14, No. 4. pp. 988-994.
@article{fdc33ef63e5c4e6ebf0953b8a9851251,
title = "Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11",
abstract = "Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.",
author = "Kimberling, {W. J.} and M{\"o}ller, {C. G.} and S. Davenport and Priluck, {I. A.} and Beighton, {P. H.} and J. Greenberg and W. Reardon and Michael Weston and Kenyon, {J. B.} and Grunkemeyer, {J. A.} and {Pieke Dahl}, S. and Overbeck, {L. D.} and Blackwood, {D. J.} and Brower, {A. M.} and Hoover, {D. M.} and P. Rowland and Smith, {R. J H}",
year = "1992",
doi = "10.1016/S0888-7543(05)80121-1",
language = "English",
volume = "14",
pages = "988--994",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "4",

}

TY - JOUR

T1 - Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11

AU - Kimberling, W. J.

AU - Möller, C. G.

AU - Davenport, S.

AU - Priluck, I. A.

AU - Beighton, P. H.

AU - Greenberg, J.

AU - Reardon, W.

AU - Weston, Michael

AU - Kenyon, J. B.

AU - Grunkemeyer, J. A.

AU - Pieke Dahl, S.

AU - Overbeck, L. D.

AU - Blackwood, D. J.

AU - Brower, A. M.

AU - Hoover, D. M.

AU - Rowland, P.

AU - Smith, R. J H

PY - 1992

Y1 - 1992

N2 - Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.

AB - Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.

UR - http://www.scopus.com/inward/record.url?scp=0027058412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027058412&partnerID=8YFLogxK

U2 - 10.1016/S0888-7543(05)80121-1

DO - 10.1016/S0888-7543(05)80121-1

M3 - Article

VL - 14

SP - 988

EP - 994

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 4

ER -