@article{9296faeb27e4425a8362747922467451,
title = "Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13",
abstract = "A small proportion of breast cancer, in particular those cases arising at a young age, is due to the inheritance of dominant susceptibility genes conferring a high risk of the disease. A genomic linkage search was performed with 15 high-risk breast cancer families that were unlinked to the BRCA1 locus on chromosome 17q21. This analysis localized a second breast cancer susceptibility locus, BRCA2, to a 6-centimorgan interval on chromosome 13q12-13. Preliminary evidence suggests that BRCA2 confers a high risk of breast cancer but, unlike BRCA1, does not confer a substantially elevated risk of ovarian cancer.",
author = "Richard Wooster and Neuhausen, {Susan L.} and Jonathan Mangion and Yvette Quirk and Deborah Ford and Nadine Collins and Kim Nguyen and Sheila Seal and Thao Tran and Diane Averill and Patty Fields and Gill Marshall and Steven Narod and Lenoir, {Gilbert M.} and Henry Lynch and Jean Feunteun and Peter Devilee and Cornelisse, {Cees J.} and Menko, {Fred H.} and Daly, {Peter A.} and Wilma Ormiston and Ross McManus and Carole Pye and Lewis, {Cathryn M.} and Cannon-Albright, {Lisa A.} and Julian Peto and Ponder, {Bruce A.J.} and Skolnick, {Mark H.} and Easton, {Douglas F.} and Goldgar, {David E.} and Stratton, {Michael R.}",
note = "Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "1994",
month = sep,
day = "30",
doi = "10.1126/science.8091231",
language = "English (US)",
volume = "265",
pages = "2088--2090",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "5181",
}