Abstract
A prolonged outbreak of Citrobacter diversus central nervous system infection among hospitalized term infants, peaking in 1979, ceased with establishment of nurse-patient cohorting. The outbreak was attributed to dissemination of an epidemic strain among infants in an antiquated neonatal intensive care unit. When C. diversus colonization recurred within the new neonatal intensive care unit in 1984, cohorting and bacteriologic surveillance were reinstituted. By utilizing biotypes, plasmid profiles and antibiograms, four differentC. diversusstrains were identified circulating during 1979. Strains recovered between 1984 and 1988 from neonatal intensive care unit infants were similar to those from community-acquired sources. A strain considered avirulent in 1979 was found causing bacteremia in two infants (one with central nervous system disease) in 1984 to 1988. During cohorting C. diversus acquisition was 0.019/patient-month; after cohorting ceased it was 0.017/patient-month. Multiple source introductions appeared to occur with differentC. diversus strains, some causing infant disease. No efficacy of cohorting was evident.
| Original language | English |
|---|---|
| Pages (from-to) | 99-104 |
| Number of pages | 6 |
| Journal | Pediatric Infectious Disease Journal |
| Volume | 11 |
| Issue number | 2 |
| State | Published - 1992 |
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All Science Journal Classification (ASJC) codes
- Infectious Diseases
- Microbiology (medical)
- Pediatrics, Perinatology, and Child Health
Cite this
Long term epidemiological analysis ofCitrobacter diversus in a neonatal intensive care unit. / Goering, Richard V.; Ehrenkranz, N. Joel; Sanders, Christine C.; Sanders, W. Eugene.
In: Pediatric Infectious Disease Journal, Vol. 11, No. 2, 1992, p. 99-104.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long term epidemiological analysis ofCitrobacter diversus in a neonatal intensive care unit
AU - Goering, Richard V.
AU - Ehrenkranz, N. Joel
AU - Sanders, Christine C.
AU - Sanders, W. Eugene
PY - 1992
Y1 - 1992
N2 - A prolonged outbreak of Citrobacter diversus central nervous system infection among hospitalized term infants, peaking in 1979, ceased with establishment of nurse-patient cohorting. The outbreak was attributed to dissemination of an epidemic strain among infants in an antiquated neonatal intensive care unit. When C. diversus colonization recurred within the new neonatal intensive care unit in 1984, cohorting and bacteriologic surveillance were reinstituted. By utilizing biotypes, plasmid profiles and antibiograms, four differentC. diversusstrains were identified circulating during 1979. Strains recovered between 1984 and 1988 from neonatal intensive care unit infants were similar to those from community-acquired sources. A strain considered avirulent in 1979 was found causing bacteremia in two infants (one with central nervous system disease) in 1984 to 1988. During cohorting C. diversus acquisition was 0.019/patient-month; after cohorting ceased it was 0.017/patient-month. Multiple source introductions appeared to occur with differentC. diversus strains, some causing infant disease. No efficacy of cohorting was evident.
AB - A prolonged outbreak of Citrobacter diversus central nervous system infection among hospitalized term infants, peaking in 1979, ceased with establishment of nurse-patient cohorting. The outbreak was attributed to dissemination of an epidemic strain among infants in an antiquated neonatal intensive care unit. When C. diversus colonization recurred within the new neonatal intensive care unit in 1984, cohorting and bacteriologic surveillance were reinstituted. By utilizing biotypes, plasmid profiles and antibiograms, four differentC. diversusstrains were identified circulating during 1979. Strains recovered between 1984 and 1988 from neonatal intensive care unit infants were similar to those from community-acquired sources. A strain considered avirulent in 1979 was found causing bacteremia in two infants (one with central nervous system disease) in 1984 to 1988. During cohorting C. diversus acquisition was 0.019/patient-month; after cohorting ceased it was 0.017/patient-month. Multiple source introductions appeared to occur with differentC. diversus strains, some causing infant disease. No efficacy of cohorting was evident.
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M3 - Article
C2 - 1741205
AN - SCOPUS:0026519103
VL - 11
SP - 99
EP - 104
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
SN - 0891-3668
IS - 2
ER -