Long term epidemiological analysis ofCitrobacter diversus in a neonatal intensive care unit

Richard V. Goering, N. Joel Ehrenkranz, Christine C. Sanders, W. Eugene Sanders

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A prolonged outbreak of Citrobacter diversus central nervous system infection among hospitalized term infants, peaking in 1979, ceased with establishment of nurse-patient cohorting. The outbreak was attributed to dissemination of an epidemic strain among infants in an antiquated neonatal intensive care unit. When C. diversus colonization recurred within the new neonatal intensive care unit in 1984, cohorting and bacteriologic surveillance were reinstituted. By utilizing biotypes, plasmid profiles and antibiograms, four differentC. diversusstrains were identified circulating during 1979. Strains recovered between 1984 and 1988 from neonatal intensive care unit infants were similar to those from community-acquired sources. A strain considered avirulent in 1979 was found causing bacteremia in two infants (one with central nervous system disease) in 1984 to 1988. During cohorting C. diversus acquisition was 0.019/patient-month; after cohorting ceased it was 0.017/patient-month. Multiple source introductions appeared to occur with differentC. diversus strains, some causing infant disease. No efficacy of cohorting was evident.

Original languageEnglish
Pages (from-to)99-104
Number of pages6
JournalPediatric Infectious Disease Journal
Volume11
Issue number2
StatePublished - 1992

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Neonatal Intensive Care Units
Citrobacter koseri
Disease Outbreaks
Central Nervous System Infections
Central Nervous System Diseases
Microbial Sensitivity Tests
Bacteremia
Plasmids
Nurses

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Microbiology (medical)
  • Pediatrics, Perinatology, and Child Health

Cite this

Long term epidemiological analysis ofCitrobacter diversus in a neonatal intensive care unit. / Goering, Richard V.; Ehrenkranz, N. Joel; Sanders, Christine C.; Sanders, W. Eugene.

In: Pediatric Infectious Disease Journal, Vol. 11, No. 2, 1992, p. 99-104.

Research output: Contribution to journalArticle

Goering, Richard V. ; Ehrenkranz, N. Joel ; Sanders, Christine C. ; Sanders, W. Eugene. / Long term epidemiological analysis ofCitrobacter diversus in a neonatal intensive care unit. In: Pediatric Infectious Disease Journal. 1992 ; Vol. 11, No. 2. pp. 99-104.
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