Long‐standing remission after 25‐OH D3 treatment in a case of chronic myelomonocytic leukaemia

Leonardo Mellibovsky; Adolfo Díez; Jaume Aubia; Xavier Nogues; Encarna Pérez‐Vila; Sergi Serrano; Robert R. Recker

doi:10.1111/j.1365-2141.1993.tb03230.x

Long‐standing remission after 25‐OH D3 treatment in a case of chronic myelomonocytic leukaemia

Leonardo Mellibovsky, Adolfo Díez, Jaume Aubia, Xavier Nogues, Encarna Pérez‐Vila, Sergi Serrano, Robert R. Recker

Department of Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

This report describes a case of chronic myelomonocytic leukaemia (CMML) in whom a complete remission was achieved and sustained 15 months after treatment with 25-OH vitamin D₃. No side-effects were observed. Although vitamin D₃ has been used in the treatment of myelodysplastic syndromes, to our knowledge this is the first case of longstanding remission in a patient with CMML. This 'differentiation therapy' might be considered as a possible alternative in the management of this disease.

Original language	English (US)
Pages (from-to)	811-812
Number of pages	2
Journal	British Journal of Haematology
Volume	85
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-2141.1993.tb03230.x
State	Published - Dec 1993

All Science Journal Classification (ASJC) codes

Hematology

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title = "Long‐standing remission after 25‐OH D3 treatment in a case of chronic myelomonocytic leukaemia",

abstract = "This report describes a case of chronic myelomonocytic leukaemia (CMML) in whom a complete remission was achieved and sustained 15 months after treatment with 25-OH vitamin D3. No side-effects were observed. Although vitamin D3 has been used in the treatment of myelodysplastic syndromes, to our knowledge this is the first case of longstanding remission in a patient with CMML. This 'differentiation therapy' might be considered as a possible alternative in the management of this disease.",

author = "Leonardo Mellibovsky and Adolfo D{\'i}ez and Jaume Aubia and Xavier Nogues and Encarna P{\'e}rez‐Vila and Sergi Serrano and Recker, {Robert R.}",

year = "1993",

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AU - Mellibovsky, Leonardo

AU - Díez, Adolfo

AU - Aubia, Jaume

AU - Nogues, Xavier

AU - Pérez‐Vila, Encarna

AU - Serrano, Sergi

AU - Recker, Robert R.

PY - 1993/12

Y1 - 1993/12

N2 - This report describes a case of chronic myelomonocytic leukaemia (CMML) in whom a complete remission was achieved and sustained 15 months after treatment with 25-OH vitamin D3. No side-effects were observed. Although vitamin D3 has been used in the treatment of myelodysplastic syndromes, to our knowledge this is the first case of longstanding remission in a patient with CMML. This 'differentiation therapy' might be considered as a possible alternative in the management of this disease.

AB - This report describes a case of chronic myelomonocytic leukaemia (CMML) in whom a complete remission was achieved and sustained 15 months after treatment with 25-OH vitamin D3. No side-effects were observed. Although vitamin D3 has been used in the treatment of myelodysplastic syndromes, to our knowledge this is the first case of longstanding remission in a patient with CMML. This 'differentiation therapy' might be considered as a possible alternative in the management of this disease.

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