Malignant melanoma of the vagina-Report of 19 cases

Arthur F. Chung, Murray J. Casey, J. T. Flannery, James M. Woodruff, John L. Lewis

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100 Scopus citations

Abstract

Sixteen previously unreported cases of primary vaginal melanoma were studied, 8 from the Memorial Sloan-Kettering Cancer Center (1935 to 1976) and 8 from the Connecticut Tumor Registry (1934 to 1976). In addition, 3 previously reported cases from the former institution are updated. Local control was obtained by means of primary radical surgery in 5 of 7 patients, 3 of whom are known to have subsequently died of disseminated disease. One patient initially treated with radical surgery had a local recurrence with metastasis to a regional node, but has now survived for more than 14 years following a second radical surgical procedure. Eight patients were treated primarily with radiotherapy, and 6 have died with metastatic melanoma; another died following pelvic exenteration for persistent local disease. Only 1 patient showed evidence of transient control after radiotherapy, but this patient had a local recurrence 36 months later and died with metastases. The overall 5-year survival rate for these 19 patients was 21%.

Original languageEnglish (US)
Pages (from-to)720-727
Number of pages8
JournalObstetrics and Gynecology
Volume55
Issue number6
StatePublished - Jun 1980
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

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    Chung, A. F., Casey, M. J., Flannery, J. T., Woodruff, J. M., & Lewis, J. L. (1980). Malignant melanoma of the vagina-Report of 19 cases. Obstetrics and Gynecology, 55(6), 720-727.