Mechanism of disappearance of S3 with maturation

Marlene K. Wilken, David G. Meyers, Peter A. Laski, Frank P. Yi, Helen Starke

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


S3 is generally audible in normal children and young adults but disappears with maturation. Disappearance of the physiologic S3 has been correlated with a decrease in the rate of early diastolic left ventricular filling and subsequent deceleration of inflow, possibly resulting from maturation-associated relative left ventricular hypertrophy.1 We examined the association of the disappearance of the physiologic S3 to changes in left ventricular diastolic function with aging.

Original languageEnglish (US)
Pages (from-to)1394-1396
Number of pages3
JournalThe American Journal of Cardiology
Issue number19
StatePublished - Dec 1 1989
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Mechanism of disappearance of S3 with maturation'. Together they form a unique fingerprint.

Cite this