Mechanisms of protective action of radix Salviae miltiorrhizae (RSM) against experimental hepatic injury in rats

H. Deng; X. Ma; R. Xu; X. Chen; Y. Zhao; L. Yin; D. Han

Mechanisms of protective action of radix Salviae miltiorrhizae (RSM) against experimental hepatic injury in rats

H. Deng, X. Ma, R. Xu, X. Chen, Y. Zhao, L. Yin, D. Han

Research output: Contribution to journal › Article › peer-review

Abstract

The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hepatocytes of rats, induce liver microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver injury.

Original language	English (US)
Pages (from-to)	233-236, inside backcover
Journal	Zhongguo Zhongyao Zazhi
Volume	17
Issue number	4
State	Published - Apr 1992
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology, Toxicology and Pharmaceutics(all)
Complementary and alternative medicine
Pharmacology (medical)

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title = "Mechanisms of protective action of radix Salviae miltiorrhizae (RSM) against experimental hepatic injury in rats",

abstract = "The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hepatocytes of rats, induce liver microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver injury.",

author = "H. Deng and X. Ma and R. Xu and X. Chen and Y. Zhao and L. Yin and D. Han",

year = "1992",

month = apr,

language = "English (US)",

volume = "17",

pages = "233--236, inside backcover",

journal = "Zhongguo Zhongyao Zazhi",

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T1 - Mechanisms of protective action of radix Salviae miltiorrhizae (RSM) against experimental hepatic injury in rats

AU - Deng, H.

AU - Ma, X.

AU - Xu, R.

AU - Chen, X.

AU - Zhao, Y.

AU - Yin, L.

AU - Han, D.

PY - 1992/4

Y1 - 1992/4

N2 - The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hepatocytes of rats, induce liver microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver injury.

AB - The results indicated that RSM could significantly inhibit the lipid peroxidation of normal livers and cultured hepatocytes of rats, induce liver microsomal cytochrome P450 in normal rats, increase nucleic acids, proteins, urea and cerolloplasmin of damaged cultured hepatocytes of rats, relieve ultrastructural damage of cultured hepatocytes induced by CCl4. The pharmacological actions mentioned above should be considered as important mechanisms of RSM against liver injury.

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C2 - 1384545

AN - SCOPUS:0026850290

VL - 17

SP - 233-236, inside backcover

JO - Zhongguo Zhongyao Zazhi

JF - Zhongguo Zhongyao Zazhi

SN - 1001-5302

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ER -