TY - JOUR
T1 - Mesh compared with non-mesh methods of open groin hernia repair
T2 - Systematic review of randomized controlled trials
AU - EU Hernia Trialists Collaboration
AU - Grant, Adrian
AU - Go, Peter
AU - Fingerhut, Abe
AU - Kingsnorth, Andrew
AU - Merello, Jesùs
AU - O'Dwyer, Paddy
AU - Payne, John
AU - Scott, Neil
AU - Webb, Kirsty
AU - Ross, Sue
AU - Aitola, Petri
AU - Anderberg, Bo
AU - Arvidsson, Dag
AU - Barkun, Jeffrey
AU - Bay-Nielsen, Morten
AU - Beets, Geerard
AU - Bittner, Reinhard
AU - Bringman, Sven
AU - Castoro, Carlo
AU - Champault, Gerard
AU - Dirksen, Carmen
AU - Filipi, Charles
AU - Fitzgibbons, Robert
AU - Girão, Ricardo
AU - Hatzitheoklitos, Efthimios
AU - Hauters, Philippe
AU - Heikkinen, Timo
AU - Jeekel, Hans
AU - Johansson, Bo
AU - Kald, Anders
AU - Kehlet, Henrik
AU - Khoury, Najib
AU - Klingler, Anton
AU - Kozol, Robert
AU - Leibl, B.
AU - Macintyre, Ian
AU - McGillicuddy, James
AU - Maddern, Guy
AU - Millat, Bertrand
AU - Nilsson, Erik
AU - Nordin, Pär
AU - Paganini, Alessandro
AU - Pappalardo, Giuseppe
AU - Pedrós, Joan Sala
AU - Schmitz, R.
AU - Schwarz, Andreas
AU - Shah, Siegfried
AU - Simmermacher, Robert
AU - Sledzinski, Zbigniew
AU - Stoker, David
PY - 2000
Y1 - 2000
N2 - Background: Open tension-free methods of groin hernia repair have been widely adopted despite little rigorous evaluation. Methods: Information was assimilated from all randomized or quasi-randomized trials comparing open mesh with open non-mesh methods to assess benefits and safety. Electronic databases were searched and members of the EU Hernia Trialists Collaboration consulted to identify trials. Prespecified data items were extracted from reports, and quantitative or, if not possible, qualitative meta-analysis was performed. Results: Fifteen eligible trials, which included 4005 participants, were identified. There were similar numbers of complications in each group, with few data to address short-term pain and length of stay in hospital. Return to usual activities was quicker in the mesh group for seven of ten trials (P not significant). There were fewer reported recurrences in the mesh groups: overall 21 (1.4 per cent) of 1513 versus 72 (4.4 per cent) of 1634 (odds ratio 0.39 (95 per cent confidence interval 0.25-0.59); P < 0.001). Conclusion: Although the rigorous search maximized trial identification, formal meta-analysis was limited by the variation in trial reporting. Within the data available, mesh repair was associated with fewer recurrences.
AB - Background: Open tension-free methods of groin hernia repair have been widely adopted despite little rigorous evaluation. Methods: Information was assimilated from all randomized or quasi-randomized trials comparing open mesh with open non-mesh methods to assess benefits and safety. Electronic databases were searched and members of the EU Hernia Trialists Collaboration consulted to identify trials. Prespecified data items were extracted from reports, and quantitative or, if not possible, qualitative meta-analysis was performed. Results: Fifteen eligible trials, which included 4005 participants, were identified. There were similar numbers of complications in each group, with few data to address short-term pain and length of stay in hospital. Return to usual activities was quicker in the mesh group for seven of ten trials (P not significant). There were fewer reported recurrences in the mesh groups: overall 21 (1.4 per cent) of 1513 versus 72 (4.4 per cent) of 1634 (odds ratio 0.39 (95 per cent confidence interval 0.25-0.59); P < 0.001). Conclusion: Although the rigorous search maximized trial identification, formal meta-analysis was limited by the variation in trial reporting. Within the data available, mesh repair was associated with fewer recurrences.
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U2 - 10.1046/j.1365-2168.2000.01539.x
DO - 10.1046/j.1365-2168.2000.01539.x
M3 - Review article
C2 - 10931018
AN - SCOPUS:0033916062
VL - 87
SP - 854
EP - 859
JO - Netherlands Journal of Surgery
JF - Netherlands Journal of Surgery
SN - 0007-1323
IS - 7
ER -