Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy

S. Omar Ahmad; Keli Mu; Samuel A. Scott

doi:10.1016/S0304-3940(01)02218-2

Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy

S. Omar Ahmad, Keli Mu, Samuel A. Scott

Department of Occupational Therapy

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.

Original language	English (US)
Pages (from-to)	153-156
Number of pages	4
Journal	Neuroscience Letters
Volume	312
Issue number	3
DOIs	https://doi.org/10.1016/S0304-3940(01)02218-2
State	Published - Oct 26 2001

All Science Journal Classification (ASJC) codes

Neuroscience(all)

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abstract = "Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.",

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