Abstract
Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.
| Original language | English |
|---|---|
| Pages (from-to) | 153-156 |
| Number of pages | 4 |
| Journal | Neuroscience Letters |
| Volume | 312 |
| Issue number | 3 |
| DOIs | |
| State | Published - Oct 26 2001 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Neuroscience(all)
Cite this
Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy. / Ahmad, S. Omar; Mu, Keli; Scott, Samuel A.
In: Neuroscience Letters, Vol. 312, No. 3, 26.10.2001, p. 153-156.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy
AU - Ahmad, S. Omar
AU - Mu, Keli
AU - Scott, Samuel A.
PY - 2001/10/26
Y1 - 2001/10/26
N2 - Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.
AB - Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.
UR - http://www.scopus.com/inward/record.url?scp=0035955501&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035955501&partnerID=8YFLogxK
U2 - 10.1016/S0304-3940(01)02218-2
DO - 10.1016/S0304-3940(01)02218-2
M3 - Article
C2 - 11602333
AN - SCOPUS:0035955501
VL - 312
SP - 153
EP - 156
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 3
ER -