Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy

S. Omar Ahmad, Keli Mu, Samuel A. Scott

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalNeuroscience Letters
Volume312
Issue number3
DOIs
StatePublished - Oct 26 2001

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Pallidotomy
Parkinson Disease
Meta-Analysis
Activities of Daily Living
Sample Size
Research Design
Quality of Life
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy. / Ahmad, S. Omar; Mu, Keli; Scott, Samuel A.

In: Neuroscience Letters, Vol. 312, No. 3, 26.10.2001, p. 153-156.

Research output: Contribution to journalArticle

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