Methods for reproducible in vivo apparent velocity in cancellous bone

G. Brandenburger, L. Avioli, C. Chestnut, R. Heaney, S. McDougall, C. Olson, R. Recker, C. Turner

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations


The apparent velocity of ultrasound (AVU) yields clinically useful information about bone fragility. AVU is measured at the patella using a small, hand-held probe consisting of a pair of identical, wideband transducers affixed to a digital caliper capable of measuring the width of the bone. The apparent velocity of ultrasound transmission is determined by dividing the measured bone width by the time of flight of the transmitted ultrasound signal. The resulting measurement variability is 2%. An approach for further reducing variability using the arrival time derived from the first zero crossing (ZC), instead of the leading edge, is described. This produces a significant reduction in the variability caused by noise, dispersion of the leading edge, and multipath propagation. Results from a 2-year clinical study of 273 women show a reduction of variability from 41 M/s to 31 M/s. Theory, methods, and clinical results are presented.

Original languageEnglish (US)
Pages (from-to)1359-1361
Number of pages3
JournalUltrasonics Symposium Proceedings
StatePublished - Dec 1 1990
EventProceedings of the IEEE 1990 Ultrasonics Symposium - Honolulu, HI, USA
Duration: Dec 4 1990Dec 7 1990

All Science Journal Classification (ASJC) codes

  • Engineering(all)


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