Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

William M. Grady; Joseph Willis; Parry J. Guilford; Anita K. Dunbier; Tumi T. Toro; Henry Lynch; Georgia Wiesner; Kelly Ferguson; Charis Eng; Jae Gahb Park; Seong Jin Kim; Sanford Markowitz

doi:10.1038/79120

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

William M. Grady, Joseph Willis, Parry J. Guilford, Anita K. Dunbier, Tumi T. Toro, Henry Lynch, Georgia Wiesner, Kelly Ferguson, Charis Eng, Jae Gahb Park, Seong Jin Kim, Sanford Markowitz

Department of Preventive Medicine

Research output: Contribution to journal › Article › peer-review

374 Scopus citations

Original language	English (US)
Pages (from-to)	16-17
Number of pages	2
Journal	Nature genetics
Volume	26
Issue number	1
DOIs	https://doi.org/10.1038/79120
State	Published - Sep 2000

All Science Journal Classification (ASJC) codes

Genetics

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10.1038/79120

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title = "Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer",

author = "Grady, {William M.} and Joseph Willis and Guilford, {Parry J.} and Dunbier, {Anita K.} and Toro, {Tumi T.} and Henry Lynch and Georgia Wiesner and Kelly Ferguson and Charis Eng and Park, {Jae Gahb} and Kim, {Seong Jin} and Sanford Markowitz",

note = "Funding Information: We thank A. Rajput and H. Hampel. This work was supported by PHS grants KO8 CA77676 (W.M.G.), RO1 CA67409, RO1 CA72160 (S.M.), P30 CA43703, P30CA16058, CA8485 and DK20593, and by the Health Research Council of New Zealand (P.J.G.). S.M. is an associate investigator of the Howard Hughes Medical Institute. Funding Information: of DNA samples; C. Searby and H. Naik for technical assistance; and R. Swiderski for collection of RNA and assistance with northern-blot analysis. This work was supported in part by NIH grant EY11298 and the Foundation Fighting Blindness (V.C.S. and E.M.S.). V.C.S. is an associate investigator of the Howard Hughes Medical Institute.",

year = "2000",

month = sep,

doi = "10.1038/79120",

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T1 - Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

AU - Grady, William M.

AU - Willis, Joseph

AU - Guilford, Parry J.

AU - Dunbier, Anita K.

AU - Toro, Tumi T.

AU - Lynch, Henry

AU - Wiesner, Georgia

AU - Ferguson, Kelly

AU - Eng, Charis

AU - Park, Jae Gahb

AU - Kim, Seong Jin

AU - Markowitz, Sanford

N1 - Funding Information: We thank A. Rajput and H. Hampel. This work was supported by PHS grants KO8 CA77676 (W.M.G.), RO1 CA67409, RO1 CA72160 (S.M.), P30 CA43703, P30CA16058, CA8485 and DK20593, and by the Health Research Council of New Zealand (P.J.G.). S.M. is an associate investigator of the Howard Hughes Medical Institute. Funding Information: of DNA samples; C. Searby and H. Naik for technical assistance; and R. Swiderski for collection of RNA and assistance with northern-blot analysis. This work was supported in part by NIH grant EY11298 and the Foundation Fighting Blindness (V.C.S. and E.M.S.). V.C.S. is an associate investigator of the Howard Hughes Medical Institute.

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Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

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