Misuse of Laboratory Tests and Diagnostic Procedures

Robert E. Sandstrom, Marc Rendell, Don R. Lipsitt, Paul F. Griner, Robert J. Glaser

Research output: Contribution to journalLetter


To the Editor: The Sounding Board article (Nov. 18 issue)1 by Griner and Glaser should not go unquestioned. The authors opine that the prevalence of marked electrolyte disturbances in healthy persons not receiving medication approaches 1 in 1000. They argue that the electrolyte component of the SMA-6 is therefore not useful in screening. I am not surprised that the prevalence of abnormalities in the population, as defined, would be 1 in 1000. The population the authors describe is of the type that, if we are lucky, we try to employ for establishing normal ranges. It is unclear to me that.

Original languageEnglish (US)
Pages (from-to)1035-1036
Number of pages2
JournalNew England Journal of Medicine
Issue number17
Publication statusPublished - Apr 28 1983
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Sandstrom, R. E., Rendell, M., Lipsitt, D. R., Griner, P. F., & Glaser, R. J. (1983). Misuse of Laboratory Tests and Diagnostic Procedures. New England Journal of Medicine, 308(17), 1035-1036. https://doi.org/10.1056/NEJM198304283081720