Abstract
Detection of extended-spectrum β-lactamases (ESBLs) in AmpC-producing Enterobacteriaceae is problematic. A modification of the double-disk test (MDDT) has been developed for successful detection of ESBLs in gram-negative bacilli producing well-characterized β-lactamases as well as 212 clinical isolates of Enterobacter cloacae, Enterobacter aerogenes, Serratia marcescens, and Citrobacter freundii. MDDT accurately differentiated between ESBL producers and derepressed chromosomal AmpC mutants. MDDT provides a cost-effective alternative approach for clinical microbiology laboratories for routine susceptibility testing with simultaneous detection of ESBLs in Enterobacteriaceae.
Original language | English (US) |
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Pages (from-to) | 3933-3935 |
Number of pages | 3 |
Journal | Journal of clinical microbiology |
Volume | 41 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2003 |
All Science Journal Classification (ASJC) codes
- Microbiology (medical)