Molindone and hepatotoxicity

S. C. Bhatia, L. E. Banta, D. W. Ehrlich

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

An adolescent male with chronic schizophrenic disorder, paranoid type, was treated with molindone. He developed hepatotoxicity in the early treatment phase as evidenced by flu-like symptoms and laboratory abnormalities of liver functions. These symptoms and his hepatic functions improved on discontinuing molindone. Similar liver function trends were seen on reintroduction and subsequent withdrawal of the drug. Hepatic hypersensitivity has not been reported previously with the use of this drug. It is suggested that clinicians should be aware of this association and should assess hepatic functions in patients who develop a prodromal flu-like syndrome with this drug, especially in the early treatment phase.

Original languageEnglish (US)
Pages (from-to)744-746
Number of pages3
JournalDrug Intelligence and Clinical Pharmacy
Volume19
Issue number10
DOIs
StatePublished - 1985

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

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