Mullerian adenosarcoma of the uterus. Ultrastructure before and after radiation therapy

I. Damjanov, Murray J. Casey, R. M. Maenza, A. W. Kennedy

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A case of mullerian adenosarcoma arising in the endometrium was studied by light and electron microscopy before and after radiation treatment. The tumor was composed of malignant stroma containing undifferentiated mesenchymal cells admixed with mature fibroblasts and other cells that contained crystalloids. The surface epithelium was lined by epithelial cells with and without cilia, similar to the normal surface epithelium cells of the uterus. High-dose therapeutic irradiation eliminated the undifferentiated mesenchymal cells from the tumor but did not alter the morphology of other epithelial and mesenchymal elements. The immaturity of mesenchymal cells and their radiosensitivity coupled with the ultrasonographic evidence of growth of the tumor point to the probable malignant nature of this neoplasm.

Original languageEnglish
Pages (from-to)96-103
Number of pages8
JournalAmerican Journal of Clinical Pathology
Volume70
Issue number1
StatePublished - 1978
Externally publishedYes

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Radiotherapy
Neoplasms
Adenosarcoma
Epithelium
Cilia
Radiation Tolerance
Endometrium
Uterus
Electron Microscopy
Fibroblasts
Epithelial Cells
Adenosarcoma of the uterus
Radiation
Light
Therapeutics
Growth

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Mullerian adenosarcoma of the uterus. Ultrastructure before and after radiation therapy. / Damjanov, I.; Casey, Murray J.; Maenza, R. M.; Kennedy, A. W.

In: American Journal of Clinical Pathology, Vol. 70, No. 1, 1978, p. 96-103.

Research output: Contribution to journalArticle

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