Abstract
A case of mullerian adenosarcoma arising in the endometrium was studied by light and electron microscopy before and after radiation treatment. The tumor was composed of malignant stroma containing undifferentiated mesenchymal cells admixed with mature fibroblasts and other cells that contained crystalloids. The surface epithelium was lined by epithelial cells with and without cilia, similar to the normal surface epithelium cells of the uterus. High-dose therapeutic irradiation eliminated the undifferentiated mesenchymal cells from the tumor but did not alter the morphology of other epithelial and mesenchymal elements. The immaturity of mesenchymal cells and their radiosensitivity coupled with the ultrasonographic evidence of growth of the tumor point to the probable malignant nature of this neoplasm.
| Original language | English |
|---|---|
| Pages (from-to) | 96-103 |
| Number of pages | 8 |
| Journal | American Journal of Clinical Pathology |
| Volume | 70 |
| Issue number | 1 |
| State | Published - 1978 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
Cite this
Mullerian adenosarcoma of the uterus. Ultrastructure before and after radiation therapy. / Damjanov, I.; Casey, Murray J.; Maenza, R. M.; Kennedy, A. W.
In: American Journal of Clinical Pathology, Vol. 70, No. 1, 1978, p. 96-103.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mullerian adenosarcoma of the uterus. Ultrastructure before and after radiation therapy
AU - Damjanov, I.
AU - Casey, Murray J.
AU - Maenza, R. M.
AU - Kennedy, A. W.
PY - 1978
Y1 - 1978
N2 - A case of mullerian adenosarcoma arising in the endometrium was studied by light and electron microscopy before and after radiation treatment. The tumor was composed of malignant stroma containing undifferentiated mesenchymal cells admixed with mature fibroblasts and other cells that contained crystalloids. The surface epithelium was lined by epithelial cells with and without cilia, similar to the normal surface epithelium cells of the uterus. High-dose therapeutic irradiation eliminated the undifferentiated mesenchymal cells from the tumor but did not alter the morphology of other epithelial and mesenchymal elements. The immaturity of mesenchymal cells and their radiosensitivity coupled with the ultrasonographic evidence of growth of the tumor point to the probable malignant nature of this neoplasm.
AB - A case of mullerian adenosarcoma arising in the endometrium was studied by light and electron microscopy before and after radiation treatment. The tumor was composed of malignant stroma containing undifferentiated mesenchymal cells admixed with mature fibroblasts and other cells that contained crystalloids. The surface epithelium was lined by epithelial cells with and without cilia, similar to the normal surface epithelium cells of the uterus. High-dose therapeutic irradiation eliminated the undifferentiated mesenchymal cells from the tumor but did not alter the morphology of other epithelial and mesenchymal elements. The immaturity of mesenchymal cells and their radiosensitivity coupled with the ultrasonographic evidence of growth of the tumor point to the probable malignant nature of this neoplasm.
UR - http://www.scopus.com/inward/record.url?scp=0018198803&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018198803&partnerID=8YFLogxK
M3 - Article
VL - 70
SP - 96
EP - 103
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
SN - 0002-9173
IS - 1
ER -