Multiple primary cancers and prolonged survival

Familial colonic and endometrial cancers

Henry T. Lynch, Wadi A. Bardawil, Randall E. Harris, Patrick M. Lynch, Hoda A. Guirgis, Jane F. Lynch

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We describe features of multiple cancers in a small kindred wherein a cluster of tumors affecting various anatomic sites has been observed among eight direct-line relatives. Three of these individuals have had two or more primary malignancies, and one woman showed a remarkable tolerance to invasive cancer, having had four histologically verified neoplasms (cancers of the ovary, endometrium, and colon, and myelogenous leukemia). The constellation of tumors occurring at an early age among relatives of this kindred supports a genetic etiology.

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalDiseases of the Colon and Rectum
Volume21
Issue number3
DOIs
StatePublished - Apr 1978

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Endometrial Neoplasms
Colonic Neoplasms
Survival
Neoplasms
Myeloid Leukemia
Ovarian Neoplasms

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Multiple primary cancers and prolonged survival : Familial colonic and endometrial cancers. / Lynch, Henry T.; Bardawil, Wadi A.; Harris, Randall E.; Lynch, Patrick M.; Guirgis, Hoda A.; Lynch, Jane F.

In: Diseases of the Colon and Rectum, Vol. 21, No. 3, 04.1978, p. 165-168.

Research output: Contribution to journalArticle

Lynch, Henry T. ; Bardawil, Wadi A. ; Harris, Randall E. ; Lynch, Patrick M. ; Guirgis, Hoda A. ; Lynch, Jane F. / Multiple primary cancers and prolonged survival : Familial colonic and endometrial cancers. In: Diseases of the Colon and Rectum. 1978 ; Vol. 21, No. 3. pp. 165-168.
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