Abstract
Approximately 5 to 6 percent of the total colorectal cancer burden is accounted for by hereditary nonpolyposis colorectal cancer (HNPCC). Because clinical premonitory signs such as those seen in familial polyposis coli (FPC) are lacking, the clinician must recognize clinical findings and family history typical of HNPCC. The authors have described colorectal cancer expression from a survey of ten HNPCC kindreds. Kindred members with colorectal cancer differed significantly (P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 439-444 |
| Number of pages | 6 |
| Journal | Diseases of the Colon & Rectum |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 1988 |
All Science Journal Classification (ASJC) codes
- Gastroenterology
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Cite this
Lynch, H. T., Watson, P., Lanspa, S. J., Marcus, J., Smyrk, T., Fitzgibbons, R. J., Kriegler, M., & Lynch, J. F. (1988). Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). Diseases of the Colon & Rectum, 31(6), 439-444. https://doi.org/10.1007/BF02552613