Abstract
Approximately 5 to 6 percent of the total colorectal cancer burden is accounted for by hereditary nonpolyposis colorectal cancer (HNPCC). Because clinical premonitory signs such as those seen in familial polyposis coli (FPC) are lacking, the clinician must recognize clinical findings and family history typical of HNPCC. The authors have described colorectal cancer expression from a survey of ten HNPCC kindreds. Kindred members with colorectal cancer differed significantly (P
| Original language | English |
|---|---|
| Pages (from-to) | 439-444 |
| Number of pages | 6 |
| Journal | Diseases of the Colon and Rectum |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1988 |
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All Science Journal Classification (ASJC) codes
- Gastroenterology
Cite this
Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). / Lynch, Henry T.; Watson, Patrice; Lanspa, Stephen J.; Marcus, Joseph; Smyrk, Tom; Fitzgibbons, Robert Joseph; Kriegler, Mary; Lynch, Jane F.
In: Diseases of the Colon and Rectum, Vol. 31, No. 6, 06.1988, p. 439-444.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II)
AU - Lynch, Henry T.
AU - Watson, Patrice
AU - Lanspa, Stephen J.
AU - Marcus, Joseph
AU - Smyrk, Tom
AU - Fitzgibbons, Robert Joseph
AU - Kriegler, Mary
AU - Lynch, Jane F.
PY - 1988/6
Y1 - 1988/6
N2 - Approximately 5 to 6 percent of the total colorectal cancer burden is accounted for by hereditary nonpolyposis colorectal cancer (HNPCC). Because clinical premonitory signs such as those seen in familial polyposis coli (FPC) are lacking, the clinician must recognize clinical findings and family history typical of HNPCC. The authors have described colorectal cancer expression from a survey of ten HNPCC kindreds. Kindred members with colorectal cancer differed significantly (P
AB - Approximately 5 to 6 percent of the total colorectal cancer burden is accounted for by hereditary nonpolyposis colorectal cancer (HNPCC). Because clinical premonitory signs such as those seen in familial polyposis coli (FPC) are lacking, the clinician must recognize clinical findings and family history typical of HNPCC. The authors have described colorectal cancer expression from a survey of ten HNPCC kindreds. Kindred members with colorectal cancer differed significantly (P
UR - http://www.scopus.com/inward/record.url?scp=0023886544&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023886544&partnerID=8YFLogxK
U2 - 10.1007/BF02552613
DO - 10.1007/BF02552613
M3 - Article
VL - 31
SP - 439
EP - 444
JO - Diseases of the Colon and Rectum
JF - Diseases of the Colon and Rectum
SN - 0012-3706
IS - 6
ER -