Natural polyphenols: Potential in the prevention of sexually transmitted viral infections

Abhijit A. Date, Christopher J. Destache

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Sexually transmitted viral infections represent a major public health concern due to lack of effective prevention strategies. Efforts are ongoing to develop modalities that can enable simultaneous prevention of multiple sexually transmitted infections. In the present review, we discuss the potential of natural polyphenols to prevent sexually transmitted viral infections. The review gives an account of various in vitro and in vivo studies carried out on epigallocatechin gallate, theaflavins (black tea polyphenols), resveratrol, genistein and curcumin to highlight their potential to prevent sexually transmitted infections caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus).

Original languageEnglish (US)
Pages (from-to)333-341
Number of pages9
JournalDrug Discovery Today
Volume21
Issue number2
DOIs
StatePublished - Jan 1 2016

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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