Necrotizing soft-tissue infections

Eric J. Kuncir, Areti Tillou, Charles R. St. Hill, Patrizio Petrone, Brian Kimbrell, Juan A. Asensio

Research output: Contribution to journalReview article

29 Scopus citations


It has been more than 130 years since NSTIs were first described. Despite the development of various classification systems and progress in surgical management, these infections continue to have high mortality and pose enormous diagnostic and therapeutic challenges. For optimal outcome, treatment involves rapid institution of appropriate antibiotic coverage and early wide surgical debridement. Recovery requires aggressive resuscitation, postoperative nutritional support and wound care that is similar to the care of burn patients in many respects. The entire therapeutic process requires a well-prepared and coordinated team of health care professionals including EPs, general, orthopedic, and other specialist surgeons, infectious disease consultants, specially trained nursing staff, and physical therapists.

Original languageEnglish
Pages (from-to)1075-1087
Number of pages13
JournalEmergency Medicine Clinics of North America
Issue number4
Publication statusPublished - 2003
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine
  • Nursing(all)
  • Emergency Medicine

Cite this

Kuncir, E. J., Tillou, A., St. Hill, C. R., Petrone, P., Kimbrell, B., & Asensio, J. A. (2003). Necrotizing soft-tissue infections. Emergency Medicine Clinics of North America, 21(4), 1075-1087.