Nerve-Sparing Surgery Significantly Affects Long-Term Continence After Radical Prostatectomy

Kalyana C. Nandipati, Rupesh Raina, Ashok Agarwal, Craig D. Zippe

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


Objectives: In this long-term prospective study we evaluated the factors affecting urinary continence after radical prostatectomy. Methods: In this study, we recruited 156 patients (mean age, 64.1 ± 6.7 years; follow-up, 7.8 ± 1.3 years; prostate-specific antigen [PSA] level, 9.57 ± 8.81 ng/mL) who underwent radical prostatectomy between 1995 and 1998. Long-term data were obtained on 152 patients, with 4 patients lost to follow-up. Incontinence was evaluated by the number of pads per day. Follow-up data were collected at 3, 6, 12, and 24 months and annually. The multivariate analysis included the following variables: preoperative PSA levels, nerve-sparing (NS) status (bilateral NS, unilateral NS, and non-NS), and age at the time of operation (≤65 or >65 years). Results: With a mean follow-up of 7.8 ± 1.3 years, the overall incontinence rate was 17.7% (27 of 152). The incontinence rates were significantly higher in the non-NS group (18 of 61) compared with the bilateral NS group (6 of 66; P 0.05). When stratified by the NS status, the bilateral NS group had a significant improvement in overall continence. The association between age and incontinence was significant: P

Original languageEnglish (US)
Pages (from-to)1127-1130
Number of pages4
Issue number6
StatePublished - Dec 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Urology


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